>eye-nematode-enoplae AAF36101 eye globin [Mermis nigrescens].
-----------------------------------MVVNLDIL-RAQLAKLPI----NEF
NGP-----KFYVHMFSSQPDWRNYF-----KG-SEAI-KPEEVPTCPRFLRQGQRVLLSM
ELMIELADK-PQLFD---AYVRDLL-DKHKQIK--GIDYDLYSAFF-DVWYGYLSKIIG-
--MSD-KEKKEWEAFRVELFLPAVKKYIAGW---------------------
>bodywall-nematode-mermis AAF35435 body wall globin [Mermis nigrescens].
-----------------------------------MVVNLDII-RAQLAKLPI----NEI
NGP-----KFYVHMFSTQPDLRNFF-----KG-SENI-KPEEVPASARFLRQGQRLLLSM
ELMIELADK-LQLFE---PYVREML-DKHKRFK--GIDYDLYNAFF-DIWYGYLSKVIG-
--LSD-QEKKEWEAFKVELFLPAVKKYIGGW---------------------
>pseudocoelomic-nematode-toxocara AAL56430 pseudocoelomic globin [Toxocara canis].
-----------MRSFALFAFALVLATVSAE--TKRELCMKSLK-DVHVGTGDH----AKQ
CGI-----DLYKHMFEHYPDLRKFF-----KN--RENYTAEDVQKDEFFAKQGQKILLAC
HVLCATVDD-METFN---AYSHEVL-DRHERDH-VELPASAWTDFW-KIFIEYLEKKMT-
--VDE-ATKNAWMEIG-KDFATAVGQHESSHSH-------------------
>intracellular-nematode-toxocara AAL56429 intracellular globin [Toxocara canis].
---------------------------------MATACLKSLE-SAQCGTCDK----AIE
NGT-----GFYALLFDKHPELRHYF-----KG-NENL-TGAEVKKSEHFKKQGQTLLLAC
HVLAHLEND-PSSFN---AYCREII-DRHLRAN-VHLDPKLWTAFW-PIWLDYLATKTT-
--VDD-ATKNAWLALG-KKFADECCNHLKNSGQPH-----------------
>myo-bodywall-nematode-ascaris P49672 Myoglobin (Globin, body wall isoform). Ascaris suum
---------------------------------MATACVKSLE-SVQCGTCEK----TIA
NGT-----EFYALLFDKHPDLRHYF-----KG-NENL-TGADVKKSDHFKKQGQRLLLAC
HVLAHLEND-PASFK---AYAREIV-DPHLRMS-VHLEPKLWSEFW-PIWLDYLSTKES-
--VDD-ATKNAWLALG-KKFSDECLDHLKNLGQPH-----------------
>nematode1 AAB28512 globin [Caenorhabditis elegans].
------------------------MSMNRQ--EISDLCVKSLE-GRMVGTEAQ----NIE
NGN-----AFYRYFFTNFPDLRVYF-----KG-AEKY-TADDVKKSERFDKQGQRILLAC
HLLANVYTN-EEVFK---GYVRETI-NRHRIYK---MDPALWMAFF-TVFTGYLESV---
GCLND-QQKAAWMALG-KEFNAESQTHLKNSNLPHV----------------
>intracellular-nematode-syngamus AAL56427 intracellular globin [Syngamus trachea].
-------------------------MLTPC--EVKKHVKNSLE-YAPIGKTPE----EIQ
NGK-----DFYKHMFTHHPDLRRYF-----KG-AESF-TADDVQKSERFEKQGQRILLAV
YILADTFDD-EQTFR---AYARETV-NRHRQFK---MDPSLWSAFF-TVFVNFLETRGS-
--LTD-DQKKAWAQLC-KVFDEECQSHLKTLGLPHC----------------
>cuticular-nematode-p P51536 Globin, cuticular isoform precursor. Nippostrongylus brasiliensis
----------MLWFVAVCFAIASVSAMSPA--DVKKHTVESMK-AVPV--GRD----KAQ
NGI-----DFYKFFFTHHKDLRKFF-----KG-AENF-GADDVQKSKRFEKQGTALLLAV
HVLANVYDN-QAVFH---GFVRELM-NRHEKRG---VDPKLWKIFFDDVWVPFLESKGA-
-KLSG-DAKAAWKELN-KNFNSEAQHQLEKLGLPHA----------------
>cuticle-nematode-syngamus AAL56426 cuticle globin [Syngamus trachea].
---MSSQLAPTTFFAFLFLACLSAVQVSGMAAADVKKHVVDSLVNVPL--GND------Q
TGK-----DFYKYFFTNHPDLRKYF-----KG-FETF-TADDVQKSEKFRTLGNAFILAI
HIVANTYDN-EPVFR---AYVRDNI-ARHVERG---LEPSLWKDFW-KIWTAFLESKGT-
-TLSA-DDKAAWEALR-DRFNDESQKELAKRGLPHA----------------
>myo-bodywall-nematode-nippo  P51535 Myoglobin (Globin, body wall isoform). Nippostrongylus brasiliensis
-----------------------------M--ADVKKNCLASLSLAPI-SKAQ----QAQ
VGK-----DFYKFFFTNHPDLRKYF-----KG-AENF-TADDVQKSDRFEKLGSGLLLSV
HILANTFDN-EDVFR---AFCRETI-DRHVGRG---LDPALWKAFW-SVWVAFLESKGG-
--VSG-DQKAAWDKLG-TVFNDECQHQLAKHGLPHL----------------
>unknown-platyhelminthes AAP06216 similar to trematode hemoglobin from Paramphistomum Epiclitum [Schistosoma japonicum].
-------------------------KMAAV--TQSQVDHLITE-LEP---HVDTEAHKLE
LGL-----KVYECFLKDRPEYICKF-----SR-LQGL-DASNVAQSEGIKYYARTFVAAF
VPMIQAAAN-KCELD---KLCLEEA-ILHRTRP---VDEKIFQDSL-PIFIKIFNNLIK-
---DQ-QNKETMSKIL-TYTFTMIGSQI------------------------
>myo-platyhelminthes P80722 Globin (Myoglobin).
---------------------------MVL--TKDEFDSLLHE-LDP---KIDTEEHRME
LGL-----GAYTELFAAHPEYIKKF-----SR-LQEA-TPANVMAQDGAKYYAKTLINDL
VELLKASTD-EATLN---TAIARTATKDHKPRN---VSGAEFQTGE-PIFIKYFSHVLT-
---TP-ANQAFMEKLL-TKIFTGVAGQL------------------------
>myo-3-platyhelminthes P80721 Globin-3 (Myoglobin).
---------------------------MTL--TKHEQDILLKE-LGP---HVDTPAHIVE
TGL-----GAYHALFTAHPQYIIHF-----SR-LEGH-TIENVMQSEGIKHYARTLTEAI
VHMLKEISN-DAEVK---KIAAQYG-KDHTSRK---VTKDEFMSGE-PIFTKYFQNLVK-
---DA-EGKAAVEKFL-KHVFPMMAAEI------------------------
>myo-1-trematode AAX11352 myoglobin 1 [Paragonimus westermani].
--------------------------MAPL--TQAEVDGVVSE-LNPFLASDAK---KVE
LGL-----GAYKALLTAKPEYIQLF-----SK-LHGL-TIDNVFQSEGIKYYARTLVEDL
VKMLTAAAK-DDELQ---KVLVHSG-HQHTTRK---VTKQQFLSGE-PIFIDFFNKTLS-
---KP-ENKAAMEKFL-KHAFPVIANNI------------------------
>myo-2-trematode AAX11353 myoglobin 2 [Paragonimus westermani].
--------------------------MAVL--TQGEVDSLLAE-LGPR--MEN----LEE
FGM-----SVYKELFTAHPEYISLF-----SK-LQGL-TLDNVMQSEGIKYYGRTLATEL
KLLVANAAN-ASELE---AVVVKNS-KDHTTRN---VTSAQFLSGE-PVFIKYFNELLT-
---KD-ENKAAMEKLL-KHVMPAIASKI------------------------
>HbI-blood_clam AAB24577 hemoglobin chain I; Hb I [Barbatia virescens].
--------------------------------NKDVAQEIKDT-WPFL--KKD----MVA
NGI-----SLMIKMFEKTPESLEFF---------KRMGDLSNPKANRKLRGHGSSLMYGI
MAFVEQLDS-PSDLT---DVAGKFA-FNHVNRN---ISSFEFQWAL-VPLLEVLRERLGR
NRYRQ-ETEEAWTKLV-SVIQATLDDRKR-----------------------
>HbA-blood_clam BAA09966 alpha chain of the tetrameric hemoglobin (intracellular) [Barbatia lima].
------------MADEEQIAKAVFKEAKALCDSDAAKENLRSS-FKIL--AND----IES
SGL-----QLMKNLFTSHPDTLGYF-----AR-FKDV---SLGKQNWQLRGHAITLMYAL
MNFVDALDE-PDRLK---CVVLKFA-VNHNNRS---ISPQVFGKIN-GPMDLLLKQRMG-
KYYNR-ETANAWKQLV-GVVQAALTTPN------------------------
>IIB-ark_clam P14394 Globin-2B (Globin IIB).
--------------------PSVQDAAAQL--TADVKKDLRDS-WKVL--GSD----KKG
DGM-----ALMTTLFNDHQETIAYF---------KRMGDVSQGMANSKLRGHSITLMYAL
QNFIDQLDS-TDDLI---CVVEKFA-VNHITRK---ISGAEFGKIN-GPMKKVLAS-KN-
--FGD-KYANAWAKLV-GVVQAAL----------------------------
>Hb2-ark_clam P14394 Globin-2B (Globin IIB).
--------------------PSVQDAAAQL--TADVKKDLRDS-WKVL--GSD----KKG
DGM-----ALMTTLFNDHQETIAYF---------KRMGDVSQGMANSKLRGHSITLMYAL
QNFIDQLDS-TDDLI---CVVEKFA-VNHITRK---ISGAEFGKIN-GPMKKVLAS-KN-
--FGD-KYANAWAKLV-GVVQAAL----------------------------
>HbI-mollusc P02213 Globin-1 (Globin I) (HbI) (Dimeric hemoglobin).
--------------------PSVYDAAAQL--TADVKKDLRDS-WKVI--GSD----KKG
NGV-----ALMTTLFADNQETIGYF---------KRLGDVSQGMANDKLRGHSITLMYAL
QNFIDQLDN-PDDLV---CVVEKFA-VNHITRK---ISAAEFGKIN-GPIKKVLAS-KN-
--FGD-KYANAWAKLV-AVVQAAL----------------------------
>HbI-Anadara P02212 Globin-1 (Globin I) (HbI).
--------------------PSVQGAAAQL--TADVKKDLRDS-WKVI--GSD----KKG
NGV-----ALMTTLFADNQETIGYF---------KRLGNVSQGMANDKLRGHSITLMYAL
QNFIDQLDN-TDDLV---CVVEKFA-VNHITRK---ISAAEFGKIN-GPIKKVLASK-N-
--FGD-KYANAWAKLV-AVVQAAL----------------------------
>myo-gastropoda-biomph O77003 Globin (Myoglobin).
---------------------------MSL--SDADKKALDAS-WKKL--TAGADG-KKN
AGI-----NLVLWMFANVPNMRAQF-----SK-FNANQSDDALKGDAEFIKQVNVIVAAL
DGLLQSVNN-PGQLQ---ANLDKLA-KSHVNLK---IGLEFFGPLQ-QNIHSFIESALG-
VGAGS-DEPKAWGNLI-AAFNETLKK--------------------------
>myo-snail P02215 Globin (Myoglobin).  [Cerithidea rhizophorarum (water snail)]
----------------------------SL--QPASKSALASS-WKTL--AKDAAT-IQN
NGA-----TLFSLLFKQFPDTRNYF-----TH-FGNM-SDAEMKTTGVGKAHSMAVFAGI
GSMIDSMDD-ADCMN---GLALKLS-RNHIQRK---IGASRFGEMR-QVFPNFLDEALG-
GGASG-DVKGAWDALL-AYLQDNKQAQAL-----------------------
>myo-Nassarius P31331 Globin (Myoglobin). [Nassarius mutabilis]
----------------------------GL--SAEQKTALKDS-WKIL--AANGET-MVK
NSA-----AMFGLLFEKYPDTKKHF-----KT-FDGD-HFAAMKATGMGKAHGMSVFSGL
GALVSSVDD-GECVL---GLAKKLS-RNHTARG---VTANDFKLMR-SIFGEFLDKATG-
GKATE-SMKSAWDALL-GVLIENHQ---------------------------
>myo-Busycon P02214 Globin (Myoglobin).
----------------------------GL--DGAQKTALKES-WKVL--GADGPT-MMK
NGS-----LLFGLLFKTYPDTKKHF-----KH-FDDA-TFAAMDTTGVGKAHGVAVFSGL
GSMICSIDD-DDCVB---GLAKKLS-RNHLARG---VSAADFKLLE-AVFKZFLDEATQ-
RKATD-AQKDADGALL-TMLIKAHV---------------------------
>drosophila-virilis CAJ30421 globin 1 [Drosophila virilis].
-----------------------------M--NSDELEMIKKT-WEIP--VAT----PTD
SGA-----AILTAFFNRFPSSLQKF-----P--FHNV-PLEELPSNARFRAHAGRIIRVF
DESIRVLGQ-DGDQEKLDEIWTKVA-VNHIPRR---ISRESYNQLK-EVILEVLTAACS-
--LNE-SQVETWTKLI-DHVYNIIFKAINEDGDAI-----------------
>drosophila CAB52584 globin [Drosophila melanogaster].
-----------------------------M--NSDEVQLIKKT-WEIP--VAT----PTD
SGA-----AILTQFFNRFPSNLEKF-----P--FRDV-PLEELSGNARFRAHAGRIIRVF
DESIQVLGQ-DGDLEKLDEIWTKIA-VSHIPRT---VSKESYNQLK-GVILDVLTAACS-
--LDE-SQAATWAKLV-DHVYAIIFKAIDDDGNA------------------
>drosophila-pseudo EAL28410 GA21995-PA [Drosophila pseudoobscura].
-----------------------------M--NSDEVQVIKKT-WEIP--VAT----PTD
SGA-----AILQEFFTRFPSNLEKF------S-FRDV-PLEDLSGNSRFRAHAGRIIRVF
DDSIRVLGE-EGDVEKLEEIWTKIA-VSHIPRT---ISKESYNQLK-GVILEVLTAACS-
--LDE-SQAATWAKLV-DHIYGIIFKAIDDDGNA------------------
>1-honeybee CAJ43388 globin 1 [Apis mellifera].
------MGTFLRFLGISSSDDNRIDQATGL--TERQKKLVQNT-WAVV--RKD----EVA
SGI-----AVMTAFFKKYPEYQRYF-----TA-FMDT-PLNELPANKRFQAHCAGVITAL
NNVIDFLHD-PGLME---ASLIGLV-ERHKKRG---QTKEEFQNLK-EVMLEVLRQALG-
KQYTP-EVAEAWNKTL-DMMFGKIYQVFAS----------------------
>cyto-beetle XP_974703 PREDICTED: similar to Cytoglobin [Tribolium castaneum].
------MGIITSTLSYYMTKTNDPDPITGL--TSRDRYVIQTS-WAPV--KKD----LTG
NGV-----ALLLLYFEKFPATKNYF------V-FKDV-PNEKLKTDKKFHAHCNSVMVTL
DSLIANLND-GELIV---SLLEKLG-KNHKRHG---IKDDAYDQLK-ETVIELFSSFMTK
EELET------WDKLL-KVAFSVIIKYL------------------------
>beetle XP_974723 PREDICTED: similar to CG9734-PB, isoform B [Tribolium castaneum].
------MGQLISLYKYYTTRTDDPDPLTTL--TSREVFLVQSS-WDPI--KKD----LTG
YGV-----QLLLFLFKKYPEEQQNF-----P--FRDM-PFEELGASKKFHAHCSNVMYAV
DSIIDSLKD-GELLV---NILEKIG-RNHHRNT---VKPISFWHVK-ETMLEFFKKMMND
ETLKA------WDKAL-QVAFGVVAKELDKKN--------------------
>hemo-a2-worm-polychaeta CAI56308 haemoglobin A2 chain [Arenicola marina].
------------MKSLVVLFALVAMVAAEC--GPMQRLLVKTQ-WNKVYGTSKV---RDE
AGH-----VLWKAIFAQDPETRALF-----KR------VNGDDIYSPEFMAHSARVLGGL
DIAISLLDN-QADLD---VALAHLH-VQHVERH---IPTRYFDLFK-NALMEYAPSALG-
RCFDK----TAWSSCF-DVIANGIKE--------------------------
>ec-worm-clitellata P83122 Extracellular globin-1 (Globin I) (Erythrocruorin).
----------------------------EC--DVLERFKVKHQ-WQTVFSEAH----RTE
FSL-----HFWKEFLHDHPSLVELF-----TR------VNGANIYSPEFQAHGIRVLAGL
DSVIGVLDE-IPTLT---VQLAHLK-AQHTERG---TKPEYFDLFG-KHLASHLGDELG-
THFDY----AAFRDCY-DFIASGIKP--------------------------
>hemo-c-clitellata BAC82448 hemoglobin, chain C [Macrobdella decora].
-------MLKLSVIFGFVLIGTIYATDEEC--SSADGHKVLED-WTHLWEDSDASF-KVE
FAK-----SVLLKLIEKHPEAKALF-----HE------VGVEDPSSGEFEAHVLRIFNSL
DLLITLLPN-REGLK---AASEHLG-QQHAVRH--GVVGTHFKTFL-SVLLDSLDHLLD-
-DFHL----FAWKSCL-KTLTKGIVDAVPQ----------------------
>c-worm-clitellata AAA98622 globin chain c.
------MLRQLLVLVGLAVVCLADEHEHCC--SEEDHRIVQKQ-WDILWRDTESSKIKIG
FGR-----LLLTKLAKDIPDVNDLF-----KR------VDIEHAEGPKFSAHALRILNGL
DLAINLLDD-PPALD---AALDHLA-HQHEVRE--GVQKAHFKKFG-EILATGLPQVLD-
-DYDA----LAWKSCL-KGILTKISSRLNA----------------------
>midge-4 P13579 Extracellular globin-4 (Globin IV) (Erythrocruorin) (Globin A).
-----------------------ADDEDCC--SYEDRREIRHI-WDDV--WSS----SFT
DRRVAIVRAVFDDLFKHYPTSKALF-----ER------VKIDEPESGEFKSHLVRVANGL
DLLINLLDD-TLVLQ---SHLGHLA-DQHIQRK--GVTKEYFRGIG-EAFARVLPQVLS-
-CFNV----DAWNRCF-HRLVARIAKDLP-----------------------
>HbII-Lucina P41261 Hemoglobin-2 (Hemoglobin II) (Hb II) (HbII).
---------------------------TTL--TNPQKAAIRSS-WSKF--MDN----GVS
NGQ-----GFYMDLFKAHPETLTPF-----KSLFGGL-TLAQLQDNPKMKAQSLVFCNGM
SSFVDHLDD--NMLV---VLIQKMA-KLHNNRG---IRASDLRTAY-DILIHYMEDHNH-
--MVG-GAKDAWEVFV-GFICKTLGDYMKELS--------------------
>HbIII-Lucina P41262 Hemoglobin-3 (Hemoglobin III) (Hb III).
--------------------------SSGL--TGPQKAALKSS-WSRF--MDN----AVT
NGT-----NFYMDLFKAYPDTLTPF-----KSLFEDV-SFNQMTDHPTMKAQALVFCDGM
SSFVDNLDD-HEVLV---VLLQKMA-KLHFNRG---IRIKELRDGY-GVLLRYLEDHCH-
--VEG-STKNAWEDFI-AYICRVQGDFMKERL--------------------
>myo-IIa-worm-clitellata CAI56310 myoglobin IIa [Arenicola marina].
---------------------------------ADQMAAVKAN-IAAV-KAGD----VTK
TAG-----DFFVFLFKKFPALQDKF-----PN-YKGK-SVDSLSSVATFAPHTTKVVAAV
LDLVAKAGD-AGVLA---GAAKQVV-ADHVSRG--VVSGAEYTDLF-AALVPFLAAALG-
---GA-CDQAAWTAAT-G----------------------------------
>HbI-Lucina P41260 Hemoglobin-1 (Hemoglobin I) (Hb I) (HbI) (Sulfide-reactive hemoglobin).
---------------------------MSL--SAAQKDNVKSS-WAKA--SAA----WGT
AGP-----EFFMALFDAHDDVFAKF-----SGLFKGA-AKGTVKNTPEMAAQAQSFKGLV
SNWVDNLDN-AGALE---GQCKTFA-ANHKARG---ISAGQLEAAF-KVLAGFMKSYGG-
-------DEGAWTAVA-GALMGMIRPNM------------------------
>midge-10 223141 hemoglobin CTTX.
-----------------------DPEWHTL--DAHEVEQVQAT-WKAV----------SH
DEV-----EILYTVFKAHPDIMAKF-----PK-FTGK-DLEAIKDTADFAVHASRIIGFF
GEYVTLLGS-SGNQAAIRTLLHDLG-VFHKTRG---ITKAQFGEFR-ETMTAYLKGHNK-
--WNA-DISHSWDDAF-DKAFSVIFEVLES----------------------
>midge-3-p P02229 Globin CTT-III precursor (Erythrocruorin III).
--------------MKFLILALCFAAASAL--SADQISTVQAS-FDKV----------KG
DPV-----GILYAVFKADPSIMAKF-----TQ-FAGK-DLESIKGTAPFEIHANRIVGFF
SKIIGELPN----IE---ADVNTFV-ASHKPRG---VTHDQLNNFR-AGFVSYMKAHTD-
--FAG--AEAAWGATL-DTFFGMIFSKM------------------------
>mide-1-p P02221 Globin CTT-I/CTT-IA precursor (Erythrocruorin).
-------------MKFLILALCVAAAMAGP--SGDQIAAAKAS-WNTV----------KN
NQV-----DILYAVFKANPDIQTAF-----SQ-FAGK-DLDSIKGTPDFSKHAGRVVGLF
SEVMDLLGN-DANTPTILAKAKDFG-KSHKSRA----SPAQLDNFR-KSLVVYLKGATK-
--WDS-AVESSWAPVL-DFVFSTLKNEL------------------------
>midge-1 GGICE1 globin CTT-I - midge (Chironomus thummi thummi).
----------------------------GP--SGDQIAAAKAS-WNTV----------KN
NQV-----DILYAVFKANPDIQTAF-----SQ-FAGK-DLDSIKGTPDFSKHAGRVVGLF
SEVMDLLGN-DANTPTILAKAKDFG-KSHKSRA----SPAQLDNFR-KSLVVYLKGATK-
--WDS-AVESSWAPVL-DFVFSTLKNEL------------------------
>midge-8 P02227 Globin CTT-VIII.
-------------------------AVTPM--SADQLALFKSS-WNTV----------KH
NEV-----DILYAVFKANPDIQAKF-----PQ-FAGK-DLDSIKDSADFAVHSGRIVGFF
SEVIGLIGN-PENRPALKTLIDGLA-SSHKARG---IEKAQFEEFR-ASLVDYLSHHLD-
--WND-TMKSTWDLAL-NNMFFYILHALEVAQ--------------------
>midge-6 223135 hemoglobin CTTVI.
---------------------------AVL--TTEQADLVKKT-WSTV----------KF
NEV-----DILYAVFKAYPDIMAKF-----PQ-FAGK-DLDSIKDSAAFATHATRIVSFL
SEVISLAGS-DANIPAIQNLAKELA-TSHKPRG---VSKDQFTEFR-TALFTYLKAHIN-
--FDG-PTETAWTLAL-DTTYAMLFSAMDS----------------------
>midge-7 P84296 Globin CTT-VIIB-4 precursor (Erythrocruorin).
-----------MKFFAVLALCIVGAIASPL--TADEASLVQSS-WKAV----------SH
NEV-----DILAAVFAAYPDIQAKF-----PQ-FAGK-DLASIKDTGAFATHATRIVSFL
SEVIALSGN-ASNAAAVEGLLNKLG-SDHKARG---VSAAQFGEFR-TALVSYLSNHVS-
--WGD-NVAAAWNKAL-DNTMAVAVAHL------------------------
>midge-2b AAB58932 globin II-beta [Chironomus thummi thummi].
------------MKFLVLALCIAAAVAAPL--SADEASLVRGS-WAQV----------KH
SEV-----DILYYIFKANPDIMAKF-----PQ-FAGK-DLETLKGTGQFATHAGRIVGFV
SEIVALMGN-SANMPAMETLIKDMA-ANHKARG---IPKAQFNEFR-ASLVSYLQSKVS-
--WND-SLGAAWTQGL-DNVFNMMFSYL------------------------
>midge-9 223166 hemoglobin CTTIX.
---------------------------DPV--SSDEANAIRAS-WAGV----------KH
NEV-----DILAAVFSDHPDIQARF-----PQ-FAGK-DLASIKDTGAFATHAGRIVGFI
SEIVALVGN-ESNQAAMATLINELS-TSHHNRG---ITKGQFNEFR-SSLVSYLSSHAS-
--WND-ATADAWTHGL-DNIFGMIFAHL------------------------
>myo-chiton 47115693 Globin-1 (Myoglobin I).
----------------------------GI--SADQAKALKDD-IAVV--AQN----PNG
CGK-----ALFIKMFEMNPGWVEKF-----PA-WKGK-SLDEIKASDKITNHGGKVINEL
ANWINNINS-AS------GILKSQG-TAHKGRS---IGIEYFENVL-PVIDATFAQQMG-
GAYTA-AMKDALKAAWTGVIVPGMKAGY------------------------
>leghemo-2-lupine P02240 Leghemoglobin-2 (Leghemoglobin II) Lupinus luteus.
--------------------------MGAL--TESQAALVKSS-WEEF--NAN----IPK
HTH-----RFFILVLEIAPAAKDLF-----SF-LKG--TSEVPQNNPELQAHAGKVFKLV
YEAAIQLQV-TGVVV-TDATLKNLG-SVHVSKG---VADAHFPVVK-EAILKTIKEVVG-
AKWSE-ELNSAWTIAY-DELAIVIKKEMNDAA--------------------
>leghemo-winged-bean CAA46704 leghemoglobin [Psophocarpus tetragonolobus].
--------------------------MGGF--TEKQEALVNSS-YEAF--KAN----VPQ
YSV-----VFYTSILEKAPAAKDLF-----PF-LANGVDP----TNPKLIGHAEKLFGLV
HDSAAQLRA-KGAV----VADAALG-SLHAQKG---VTDPQFVVVK-EALLKTVKEAVG-
DKWSD-ELSNAWEVAY-NELAAALKKAF------------------------
>leghemo-phaseolus BAA20415 leghemoglobin [Phaseolus vulgaris].
--------------------------MGAF--TEKQEALVNSS-WEAF--KGN----IPQ
YSV-----VFYTSILEKAPAAKNLF----------SFLANGVDPTNPKLTAHAESLFGLV
RDSAAQLRA-NGAV----VADAALG-SIHSQKA---LNDSQFLVVK-EALLKTLKEAVG-
DKWTD-ELSTALELAY-DEFAAGIKKAYA-----------------------
>leghemo-soybean CAA31859 leghemoglobin [Sesbania rostrata].
---------------------------MGF--TEKQEALVNAS-YEAF--KQN----LPG
NSV-----LFYSFILEKAPAAKGMF-----SF-LKD--SDGVPQNNPSLQAHAEKVFGLV
RDSAAQLRA-TGVVV---LADASLG-SVHVQKG---VLDPHFVVVK-EALLKTLKEAAG-
ATWSD-EVSNAWEVAY-DGLSAAIKKAMS-----------------------
>leghemo-sesbiana CAA31859 leghemoglobin [Sesbania rostrata].
---------------------------MGF--TEKQEALVNAS-YEAF--KQN----LPG
NSV-----LFYSFILEKAPAAKGMF-----SF-LKD--SDGVPQNNPSLQAHAEKVFGLV
RDSAAQLRA-TGVVV---LADASLG-SVHVQKG---VLDPHFVVVK-EALLKTLKEAAG-
ATWSD-EVSNAWEVAY-DGLSAAIKKAMS-----------------------
>leghemo-pea BAA31157 leghemoglobin [Pisum sativum].
---------------------------MGF--TEKQEALVNSS-WELF--KQN-----PS
YSV-----LFYTIILKKAPAAKGMF-----SF----LKDSAEVVDSPKLQAHAEKVFGMV
HDSAIQLRA-SGEVV---LGDATLG-AIHIQKG---VVDPHFVVVK-EALLETIKEASG-
EKWSE-ELSTAWEVAY-EGLASAIKKAMN-----------------------
>leghemo-alfalfa-1 P09187 Leghemoglobin-1 (Leghemoglobin I) Medicago sativa.
---------------------------MSF--TDKQEALVNSS-WEAF--KQN----LPR
YSV-----FFYTVVLEKAPAAKGLF-----SF----LKNSAEVQDSPQLQAHAEKVFGLV
RDSAVQLRA-TGGVV---LGDATLG-AIHVRKG---VVDPHFVVVK-EALLKTIKEAAG-
DKWSE-ELNTAWEVAY-DALATAIKKAMS-----------------------
>leghemo-alfalfa-3 P14962 Leghemoglobin-3 (Leghemoglobin III).
---------------------------MGF--TDKQEALVNSS-WESF--KQN-----PG
NSV-----LFYTIILEKAPAAKGMF-----SF----LKDSAGVQDSPKLQSHAEKVFGMV
RDSAAQLRA-TGGVV---LGDATLG-AIHIQKG---VVDPHFAVVK-EALLKTIKEVSG-
DKWSE-ELNTAWEVAY-DALATAIKKAMV-----------------------
>leghemo-1-swamp_oak P08054 Hemoglobin-1 (Hemoglobin I) Casuarina glauca.
---------------------------MAL--TEKQEALLKQS-WEVL--KQN----IPA
HSL-----RLFALIIEAAPESKYVF-----SF-LKD--SNEIPENNPKLKAHAAVIFKTI
CESATELRQ-KGHAVWDNNTLKRLG-SIHLKNK---ITDPHFEVMK-GALLGTIKEAIK-
ENWSD-EMGQAWTEAY-NQLVATIKAEMKE----------------------
>leghemo-2-swamp_oak P23244 Hemoglobin-2 (Hemoglobin II) Casuarina glauca.
---------------------MSTLEGRGF--TEEQEALVVKS-WSAM--KPN----AGE
LGL-----KFFLKIFEIAPSAQKLF-----SF-LKD--SNVPLERNPKLKSHAMSVFLMT
CESAVQLRK-AGKVTVRESSLKKLG-ASHFKHG---VADEHFEVTK-FALLETIKEAVP-
ETWSP-EMKNAWGEAY-DKLVAAIKLEMKPSS--------------------
>leghemo-rice-1 O04986 Non-symbiotic hemoglobin 1 (rHb1) (ORYsa GLB1a).
-------------MALVEDNNAV---AVSF--SEEQEALVLKS-WAIL--KKD----SAN
IAL-----RFFLKIFEVAPSASQMF-----SF-LRN--SDVPLEKNPKLKTHAMSVFVMT
CEAAAQLRK-AGKVTVRDTTLKRLG-ATHLKYG---VGDAHFEVVK-FALLDTIKEEVPA
DMWSP-AMKSAWSEAY-DHLVAAIKQEMKPAE--------------------
>leghemo-rice-2 O04985 Non-symbiotic hemoglobin 2 (rHb2) (ORYsa GLB1b).
-------------MALVEGNNGVSGGAVSF--SEEQEALVLKS-WAIM--KKD----SAN
IGL-----RFFLKIFEVAPSASQMF-----SF-LRN--SDVPLEKNPKLKTHAMSVFVMT
CEAAAQLRK-AGKVTVRDTTLKRLG-ATHFKYG---VGDAHFEVTR-FALLETIKEAVPV
DMWSP-AMKSAWSEAY-NQLVAAIKQEMKPAE--------------------
>leghemo-rice-3 AF335504 
--------------MAANGSNVVSRGAVRF--TEEQEALVLKS-WAIM--KND----SAH
IGH-----RFFLKIFEVAPSARQLF-----SF-LRN--SDVPLEKNPKLKIHAMAVFVMT
CEAAAQLRK-TGRVTVRDTTIKRLG-STHFKNG---VSDAHFEVAK-FALLETIKEAVPA
SMWSP-AMKGAWGEAY-DHLVAAIKQGMKPAAA-------------------
>leghemo-rice-4 AF335504
------------------AFASASNGAVRF--TEEQEALVLKS-WAIM--KDD----SAN
IGH-----RFFLKIFEVAPSARHLF-----SF-LRN--SDVPLEKNPNLKKHAMAVFVMT
CEAAAQLRK-TGRVTVRDTTIKRLG-STHFKNG---VSDTHFEVAR-FALLETIKDGIPA
SMWSP-EMKNAWGEAY-EHLVAAIKEGMKPVALL------------------
>neuro-zebrafish NM_13185 Danio rerio neuroglobin (ngb)
--------------------------MEKL--SEKDKGLIRDS-WESL--GKN----KVP
HGI-----VLFTRLFELDPALLTLF-----SY-STNCGDAPECLSSPEFLEHVTKVMLVI
DAAVSHLDD-LHTLE---DFLLNLG-RKHQAVG---VNTQSFALVG-ESLLYMLQSSLG-
PAYTT-SLRQAWLTMY-SIVVSAMTRGWAKNGEHKSN---------------
>neuro-chicken NM_001031551 Gallus gallus neuroglobin (NGB), mRNA
------------------------MESGML--SRTQQALIRES-WRRV--SGS----PVQ
HGV-----VLFSRLFDLDPDLLPLF----QYN-CKRFASPQECLAAPEFLDHIRKVMLVI
DAAVSHLED-LPCLE---EYLCNLG-KKHQAVG---VKVESFSTVG-ESLLYMLEKCLG-
AAFSP-DVREAWIELY-SAVVKAMQRGWEVLPEGD-----------------
>neuro-opossum NM_001035515 Monodelphis domestica neuroglobin (NGB)
-------------------------ETRRL--SGPEQELIRES-WQKV--NSN----PLQ
HGM-----ILFTRLFDLEPDLLPLF----QYN-CRQFSSPQDCLSSPEFLDHIRKVMLVI
DAAVTHVEN-LSSLE---EYLTNLG-KKHKAVG---VKLSSFSTVG-ESLLYMLEQCLG-
STFTV-TMKEAWTQLY-GAVVQAMSRGWNGE---------------------
>neuro-rat NM_033359 Rattus norvegicus neuroglobin (Ngb)
-----------------------------M--ERLESELIRQS-WRAV--SRS----PLE
HGT-----VLFSRLFALEPSLLPLF----QYN-GRQFSSPEDCLSSPEFLDHIRKVMLVI
DAAVTNVED-LSSLE---EYLATLG-RKHRAVG---VRLSSFSTVG-ESLLYMLEKCLG-
PDFTP-ATRTAWSQLY-GAVVQAMSRGWDGE---------------------
>neuro-mouse BC024263 Mus musculus neuroglobin, mRNA
-----------------------------M--ERPESELIRQS-WRVV--SRS----PLE
HGT-----VLFARLFALEPSLLPLF----QYN-GRQFSSPEDCLSSPEFLDHIRKVMLVI
DAAVTNVED-LSSLE---EYLTSLG-RKHRAVG---VRLSSFSTVG-ESLLYMLEKCLG-
PDFTP-ATRTAWSRLY-GAVVQAMSRGWDGE---------------------
>neuro-dog NM_001003356 Canis familiaris neuroglobin (NGB)
-----------------------------M--ERPEPELIRQS-WRAV--RRS----PLE
HGT-----VLFARLFDLEPDLLPLF----QYN-CRQFSSPEDCLSSPEFLDHIRKVMLVI
DTAVTNVED-LSSLE---EYLAGLG-KKHRAVG---VKLSSFSTVG-ESLLYMLEKCLG-
PAFTP-AVRAAWSQLY-GAVVQAMSRGWDGD---------------------
>neuro-human NM_021257 Homo sapiens neuroglobin (NGB)
-----------------------------M--ERPEPELIRQS-WRAV--SRS----PLE
HGT-----VLFARLFALEPDLLPLF----QYN-CRQFSSPEDCLSSPEFLDHIRKVMLVI
DAAVTNVED-LSSLE---EYLASLG-RKHRAVG---VKLSSFSTVG-ESLLYMLEKCLG-
PAFTP-ATRAAWSQLY-GAVVQAMSRGWDGE---------------------
>neuro-chimp BN000825 TPA_inf: Pan troglodytes mRNA for neuroglobin (ngb gene)
-----------------------------M--ERPEPELIRQS-WRAV--SRS----PLE
HGT-----VLFARLFALEPDLLPLF----QYN-CRQFSSPEDCLSSPEFLDHIRKVMLVI
DAAVTNVED-LSSLE---EYLASLG-RKHRAVG---VKLSSFSTVG-ESLLYMLEKCLG-
PAFTP-ATRAAWSQLY-GAVVQAMSRGWDGE---------------------
>neuro-rhesus NM_001035514 Macaca mulatta neuroglobin (NGB)
-----------------------------M--ERPEPELIRQS-WRAV--SRS----PLE
HGT-----VLFARLFALEPDLLPLF----QYN-CRQFSSPEDCLSSPEFLDHIRKVMLVI
DAAVTNVED-LSSLE---EYLASLG-RKHRAVG---VKLSSFSTVG-ESLLYMLEKCLG-
PAFTP-ATRAAWSQLY-GAVVQAMSRGWDSE---------------------
>myo-gastropoda-aplysia P14393 Globin (Myoglobin).
----------------------------AL--SAADAGLLAQS-WAPV--FAN----SDA
NGA-----SFLVALFTQFPESANFF-----ND-FKGK-SLADIQASPKLRDVSSRIFARL
NEFVSNAAD-AGKMG---SMLQQFA-TEHAGFG---VGSAQFQNVR-SMFPGFVASLSA-
----P-AADAAWNSLF-GLIISALQSAGK-----------------------
>myo-gastropoda-seahare P02211 Globin (Myoglobin).
---------------------------MSL--SAAEADLVGKS-WAPV--YAN----KDA
NGD-----AFLLSLFEKFPNNANYF-----AD-FKGK-SIADIKASPKLRDVSSRIFTRL
NEFVNNAAD-AGKMS---AMLSQFA-SEHVGFG---VGSAQFENVR-SMFPAFVASLSA-
----P-PADDAWNKLF-GLIVAALKAAGK-----------------------
>myo-Dolabella P09965 Globin (Myoglobin).
----------------------------AL--SAAEAEVVAKS-WGPV--FAN----KDA
NGD-----NFLIALFEAYPDSPNFF-----AD-FKGK-SIADIRASPKLRNVSSRIVSRL
NEFVSSAAD-AGKMA---AMLDQFS-KEHAGFG---VGSQQFQNVS-AMFPGFVASIAA-
---PPAGADAAWGKLF-GLIIDAMKKAGK-----------------------
>hemo-beta-shark P07409 Hemoglobin subunit beta (Hemoglobin beta chain) (Beta-globin).
---------------------------VHW--TGEEKALVNAV-WTKT----D----HQA
VVA-----KALERLFVVYPWTKTYF-----VK-FNGKFHASD----STVQTHAGKVVSAL
TVAYNHIDD----VK---PHFVELS-KKHYEEL--HVDPENFKLLA-NCLEVELGHALH-
KEFTP-EVQAAWSKFS-NVVVDALSKGYH-----------------------
>hemo-beta-coelacanth 227808 globin beta.
---------------------------VHW--TETERATIETV-YQKL----H----LDE
VGR-----EALTRLFIVYPWTTRYF-----KS-FGDLSSSKAIASNPKVTEHGLKVMNKL
TEAIHNLDH----IK---DLFHKLS-EKHFHEL--HVDPQNFKLLS-KCLIIVLATKLG-
KQLTP-DVQATWEKLL-SVVVAALSREYH-----------------------
>hemo-beta2-danio CAD60792 novel beta-type globin [Danio rerio].
--------------------------MVVW--TDFEKATIQDI-FAKA----D----YDV
IGP-----QALARCLIVYPWTQRYF-----AK-FGNLYNAAAILGNPMVAAHGKTVLKGL
ELAVKNMDN----IK---ATYADLS-VLHSEKL--HVDPDNFRLLA-DCLTIVVAAQMG-
AGFTP-EVQAAFQKFI-AVAVSALGRQYH-----------------------
>hemo-beta-chicken NP_990820 beta globin [Gallus gallus].
--------------------------MVHW--TAEEKQLITGL-WGKV----N----VAE
CGA-----EALARLLIVYPWTQRFF-----AS-FGNLSSPTAILGNPMVRAHGKKVLTSF
GDAVKNLDN----IK---NTFSQLS-ELHCDKL--HVDPENFRLLG-DILIIVLAAHFS-
KDFTP-ECQAAWQKLV-RVVAHALARKYH-----------------------
>HBB_HORSE
--------------------------MVQL--SGEEKAAVLAL-WDKV----N----EEE
VGG-----EALGRLLVVYPWTQRFF-----DS-FGDLSNPGAVMGNPKVKAHGKKVLHSF
GEGVHHLDN----LK---GTFAALS-ELHCDKL--HVDPENFRLLG-NVLVVVLARHFG-
KDFTP-ELQASYQKVV-AGVANALAHKYH-----------------------
>hemo-beta-human NP_000509 beta globin [Homo sapiens].
--------------------------MVHL--TPEEKSAVTAL-WGKV----N----VDE
VGG-----EALGRLLVVYPWTQRFF-----ES-FGDLSTPDAVMGNPKVKAHGKKVLGAF
SDGLAHLDN----LK---GTFATLS-ELHCDKL--HVDPENFRLLG-NVLVCVLAHHFG-
KEFTP-PVQAAYQKVV-AGVANALAHKYH-----------------------
>hemo-delta-human NP_000510 delta globin [Homo sapiens].
--------------------------MVHL--TPEEKTAVNAL-WGKV----N----VDA
VGG-----EALGRLLVVYPWTQRFF-----ES-FGDLSSPDAVMGNPKVKAHGKKVLGAF
SDGLAHLDN----LK---GTFSQLS-ELHCDKL--HVDPENFRLLG-NVLVCVLARNFG-
KEFTP-QMQAAYQKVV-AGVANALAHKYH-----------------------
>hemo-A-gamma-human NP_000550 A-gamma globin [Homo sapiens].
--------------------------MGHF--TEEDKATITSL-WGKV----N----VED
AGG-----ETLGRLLVVYPWTQRFF-----DS-FGNLSSASAIMGNPKVKAHGKKVLTSL
GDATKHLDD----LK---GTFAQLS-ELHCDKL--HVDPENFKLLG-NVLVTVLAIHFG-
KEFTP-EVQASWQKMV-TAVASALSSRYH-----------------------
>hemo-G-gamma-human NP_000175 G-gamma globin [Homo sapiens].
--------------------------MGHF--TEEDKATITSL-WGKV----N----VED
AGG-----ETLGRLLVVYPWTQRFF-----DS-FGNLSSASAIMGNPKVKAHGKKVLTSL
GDAIKHLDD----LK---GTFAQLS-ELHCDKL--HVDPENFKLLG-NVLVTVLAIHFG-
KEFTP-EVQASWQKMV-TGVASALSSRYH-----------------------
>hemo-epsilon-human P02100 Hemoglobin subunit epsilon (Hemoglobin epsilon chain) (Epsilon-globin).
--------------------------MVHF--TAEEKAAVTSL-WSKM----N----VEE
AGG-----EALGRLLVVYPWTQRFF-----DS-FGNLSSPSAILGNPKVKAHGKKVLTSF
GDAIKNMDN----LK---PAFAKLS-ELHCDKL--HVDPENFKLLG-NVMVIILATHFG-
KEFTP-EVQAAWQKLV-SAVAIALAHKYH-----------------------
>hemo-alpha-shark P07408 Hemoglobin subunit alpha (Hemoglobin alpha chain) (Alpha-globin).
----------------------------VL--SAADKTAIKHL-TGSL--RTN----AEA
WGA-----ESLARMFATTPSTKTYF-----SK-FTDF-----SANGKRVKAHGGKVLNAV
ADATDHLDN----VA---GHLDPLA-VLHGTTL--CVDPHNFPLLT-QCILVTLAAHLT-
-ELKP-ETHCALDKFL-CEVATALGSHYR-----------------------
>hemo-mu-human NP_001003938 hemoglobin mu chain [Homo sapiens].
----------------------------ML--SAQERAQIAQV-WDLI--AGH----EAQ
FGA-----ELLLRLFTVYPSTKVYF-----PH-------LSACQDATQLLSHGQRMLAAV
GAAVQHVDN----LR---AALSPLA-DLHALVL--RVDPANFPLLI-QCFHVVLASHLQ-
DEFTV-QMQAAWDKFL-TGVAVVLTEKYR-----------------------
>hemo-alpha-coelacanth 227807 globin alpha.
----------------------------GL--TAADKTLIKSI-WGKV--EKE----TEA
IGV-----EALVRLFKCFPQSKVYF-----DH-FTDL-----SPSSQKLHAHAKVVLGAL
TKAVNHLDN----IT---DTLHDIS-LVHAKKL--LVDPVNFELLG-HCLEVALAAHFA-
TDFTP-EVHLAIDKFL-YEVEKALFETYR-----------------------
>hemo-alpha-zebrafish NP_571332 hemoglobin alpha adult-1 [Danio rerio].
---------------------------MSL--SDTDKAVVKAI-WAKI--SPK----ADE
IGA-----EALARMLTVYPQTKTYF-----SH-WADL-----SPGSGPVKKHGKTIMGAV
GEAVSKIDD----LV---GGLAALS-ELHAFKL--RVDPANFKILS-HNVIVVIAMLFP-
ADFTP-EVHVSVDKFF-NNLALALSEKYR-----------------------
>hemo-alpha2-danio CAD60793 novel alpha-type globin [Danio rerio].
---------------------------MSL--SAKDKAAVKTL-WAKI--AGK----ADD
IGH-----DALSRMLIVYPQTKTYF-----SH-WKDL-----SPGSAPVRKHGKTVMGGV
AEAVSKIDD----LN---AGLLNLS-ELHAFQL--RVDPANFKILS-HNILVVLATLFP-
ADFTP-EAHVAMDKFL-SALALAMSEKYR-----------------------
>hemo-alpha-chicken NP_001004376 alpha 1 globin [Gallus gallus].
---------------------------MVL--SAADKNNVKGI-FTKI--AGH----AEE
YGA-----ETLERMFTTYPPTKTYF-----PH-------FDLSHGSAQIKGHGKKVVAAL
IEAANHIDD----IA---GTLSKLS-DLHAHKL--RVDPVNFKLLG-QCFLVVVAIHHP-
AALTP-EVHASLDKFL-CAVGTVLTAKYR-----------------------
>hemo-alpha-possum NP_001028158 hemoglobin, alpha [Monodelphis domestica].
---------------------------MVL--SAADKTNVKAA-WSKV--GGN----SGA
YMG-----EALYRTFLSFPPTKTYF-----PH-FEFS------AGSAQIKGQGQKIADAV
SLAVAHMDD----LA---TALSALS-DLHAHNL--KVDPVNFKFLC-HNVLVTLASHLG-
KDFTP-EIHASLDKFL-ALLSTVLTSKYR-----------------------
>HBA_HORSE
---------------------------MVL--SAADKTNVKAA-WSKV--GGH----AGE
YGA-----EALERMFLGFPTTKTYF-----PH-------FDLSHGSAQVKAHGKKVGDAL
TLAVGHLDD----LP---GALSNLS-DLHAHKL--RVDPVNFKLLS-HCLLSTLAVHLP-
NDFTP-AVHASLDKFL-SSVSTVLTSKYR-----------------------
>hemo-alpha-human {NP_000508,NP_000509} alpha {1,2} globin [Homo sapiens].
---------------------------MVL--SPADKTNVKAA-WGKV--GAH----AGE
YGA-----EALERMFLSFPTTKTYF-----PH-------FDLSHGSAQVKGHGKKVADAL
TNAVAHVDD----MP---NALSALS-DLHAHKL--RVDPVNFKLLS-HCLLVTLAAHLP-
AEFTP-AVHASLDKFL-ASVSTVLTSKYR-----------------------
>hemo-pi-chicken P02007 Hemoglobin subunit pi (Hemoglobin pi chain) (Pi-globin) (Hemoglobin pi' chain).
---------------------------MAL--TQAEKAAVTTI-WAKV--ATQ----IES
IGL-----ESLERLFASYPQTKTYF-----PH-------FDVSQGSVQLRGHGSKVLNAI
GEAVKNIDD----IR---GALAKLS-ELHAYIL--RVDPVNFKLLS-HCILCSVAARYP-
SDFTP-EVHAAWDKFL-SSISSVLTEKYR-----------------------
>hemo-mu-chicken NP_001004375 hemoglobin mu chain [Gallus gallus].
----------------------------ML--TAEDKKLIQQA-WEKA--ASH----QEE
FGA-----EALTRMFTTYPQTKTYF-----PH-------FDLSPGSDQVRGHGKKVLGAL
GNAVKNVDN----LS---QAMAELS-NLHAYNL--RVDPVNFKLLS-QCIQVVLAVHMG-
KDYTP-EVHAAFDKFL-SAVSAVLAEKYR-----------------------
>unknown2-hagfish AAD40480 hemoglobin [Myxine glutinosa].
---------------------MSAHGIART--TEGERAAVRAS-WAVL--MKD----YEH
AGV-----QILDKFFKANPAAKPFF-----TK-MKDLHTLEDLASSADARWHVERIIQAV
NFAVINIED-REKLS---NKFVKLS-QDHIEEF-HVTDPQYFMILS-QTILDEVEKRNG-
-GLSG-EGKSGWHKVM-TIICKMLKSKY------------------------
>I-lamprey P09967 Globin-1 (Globin I). GLB1_PETMA [Petromyzon marinus (sea lamprey)]
------------------MPIVDSGSVPAL--TAAEKATIRTA-WAPV--YAK----YQS
TGV-----DILIKFFTSNPAAQAFF-----PK-FQGLTSADQLKKSMDVRWHAERIINAV
NDAVVAMDD-TEKMS---LKLRELS-GKHAKSF--QVDPQYFKVLA-AVIVDTVL-----
------PGDAGLEKLM-SMICILLRSSY------------------------
>III-lamprey P09968 Globin-3 (Globin III). GLB3_PETMA [Petromyzon marinus (sea lamprey)]
------------------MPIVDSGSVAPL--SAAEKTKIRSA-WAPV--YSN----YET
TGV-----DILVKFFTSTPAAQEFF-----PK-FKGLTTADQLKKSADVRWHAERIINAV
NDAVVSMDD-TEKMS---MKLGDLS-GKHAKSF--QVDPQYFKVLA-AVIADTVA-----
------AGDAGFEKLM-SMICILLRSAY------------------------
>V-lamprey P02208 Globin-5 (Hemoglobin V). GLB5_PETMA [Petromyzon marinus (sea lamprey)]
------------------MPIVDTGSVAPL--SAAEKTKIRSA-WAPV--YST----YET
SGV-----DILVKFFTSTPAAQEFF-----PK-FKGLTTADQLKKSADVRWHAERIINAV
NDAVASMDD-TEKMS---MKLRDLS-GKHAKSF--QVDPQYFKVLA-AVIADTVA-----
------AGDAGFEKLM-SMICILLRSAY------------------------
>II-lamprey AF248645 Petromyzon marinus hemoglobin PMII' mRNA
------------------MPIVDTGSVAPL--SAAEKTKIRSA-WAPV--YSN----YET
SGV-----DILVKFFTSTPAAQEFF-----PK-FKGLTTADQLKKSADVRWHAERIINAV
NDAVVSMDD-TEKMS---MKLRDLS-GKHAKSF--QVDPQYFKVLA-AVIADTVA-----
------AGDAGFEKLM-SMICILLRSAY------------------------
>F1-hagfish 74922327 Globin-F1. Inshore hagfish
-------------------PIIDQGPLPTL--TDGDKKAINKI-WPKI--YKE----YEQ
YSL-----NILLRFLKCFPQAQASF-----PK-FST--KKSNLEQDPEVKHQAVVIFNKV
NEIINSMDN-QEEII---KSLKDLS-QKHKTVF--KVDSIWFKELS-SIFVSTIDGGAE-
-----------FEKLF-SIICILLRSAY------------------------
>III-hagfish P02209 Globin-3 (Hemoglobin III). Atlantic Hagfish
------------------MPITDHGQPPTL--SEGDKKAIRES-WPQI--YKN----FEQ
NSL-----AVLLEFLKKFPKAQDSF-----PK-FSA--KKSHLEQDPAVKLQAEVIINAV
NHTIGLMDK-EAAMK---KYLKDLS-TKHSTEF--QVNPDMFKELS-AVFVSTMGGKAA-
-----------YEKLF-SIIATLLRSTYDA----------------------
>unknown1-hagfish AAD40310 hemoglobin [Myxine glutinosa].
------------------MPITDQGPLPTL--SEGDKKAIRES-WPQI--YQN----FEQ
TGL-----VVLLEFLQKNPGAQQSF-----PK-FSA--TKCNLEQDNEVKWQASRIINAV
NHTIGLMDK-EAAMK---QYLKELS-AKHSSEF--QVDPKLFKELS-AIFVSTIRGKAA-
-----------YEKLF-SIICTLLRSSYDE----------------------
>myo-shark-gummy Myoglobin.
----------------------------------VDWEKVNSV-WSAV--ESD----LTA
IGQ-----NILLRLFEQYPESQNHF-----PK-FKNK-SLGELKDTADIKAQADTVLSAL
GNIVKKKGS-HS------QPVKALA-ATHITTH--KIPPHYFTKIT-TIAVDVLSEMYP-
SEMNA-QVQAAFSGAF-KIICSDIEKEYKAANFQG-----------------
>myo-shark-pj P02206 Myoglobin. Port Jackson Shark
----------------------------------TEWEHVNKV-WAVV--EPD----IPA
VGL-----AILLRLFKEHKETKDLF-----PK-FKEI-PVQQLGNNEDLRKHGVTVLRAL
GNILKQKGK-HS------TNVKELA-DTHINKH--KIPPKNFVLIT-NIAVKVLTEMYP-
SDMTG-PMQESFSKVF-TVICSDLETLYKEANFQG-----------------
>myo-chicken P02197 Myoglobin.
----------------------------GL--SDQEWQQVLTI-WGKV--EAD----IAG
HGH-----EVLMRLFHDHPETLDRF-----DK-FKGLKTPDQMKGSEDLKKHGATVLTQL
GKILKQKGN-HE------SELKPLA-QTHATKH--KIPVKYLEFIS-EVIIKVIAEKHA-
ADFGA-DSQAAMKKAL-ELFRNDMASKYKEFGFQG-----------------
>myo-mouse NP_038621 myoglobin [Mus musculus].
---------------------------MGL--SDGEWQLVLNV-WGKV--EAD----LAG
HGQ-----EVLIGLFKTHPETLDKF-----DK-FKNLKSEEDMKGSEDLKKHGCTVLTAL
GTILKKKGQ-HA------AEIQPLA-QSHATKH--KIPVKYLEFIS-EIIIEVLKKRHS-
GDFGA-DAQGAMSKAL-ELFRNDIAAKYKELGFQG-----------------
>myo-rat NP_067599 myoglobin [Rattus norvegicus].
---------------------------MGL--SDGEWQMVLNI-WGKV--EGD----LAG
HGQ-----EVLISLFKAHPETLEKF-----DK-FKNLKSEEEMKSSEDLKKHGCTVLTAL
GTILKKKGQ-HA------AEIQPLA-QSHATKH--KIPVKYLEFIS-EVIIQVLKKRYS-
GDFGA-DAQGAMSKAL-ELFRNDIAAKYKELGFQG-----------------
>myo-cow P02192 Myoglobin.
---------------------------MGL--SDGEWQLVLNA-WGKV--EAD----VAG
HGQ-----EVLIRLFTGHPETLEKF-----DK-FKHLKTEAEMKASEDLKKHGNTVLTAL
GGILKKKGH-HE------AEVKHLA-ESHANKH--KIPVKYLEFIS-DAIIHVLHAKHP-
SDFGA-DAQAAMSKAL-ELFRNDMAAQYKVLGFHG-----------------
>myo-sq-monkey P02155 Myoglobin.
----------------------------GL--SDGEWQLVLNI-WGKV--EAD----IPS
HGQ-----EVLISLFKGHPETLEKF-----DK-FKHLKSEDEMKASEELKKHGTTVLTAL
GGILKKKGQ-HE------AELKPLA-QSHATKH--KIPVKYLELIS-DAIVHVLQKKHP-
GDFGA-DAQGAMKKAL-ELFRNDMAAKYKELGFQG-----------------
>myo-horse P68082 Myoglobin.
----------------------------GL--SDGEWQQVLNV-WGKV--EAD----IAG
HGQ-----EVLIRLFTGHPETLEKF-----DK-FKHLKTEAEMKASEDLKKHGTVVLTAL
GGILKKKGH-HE------AELKPLA-QSHATKH--KIPIKYLEFIS-DAIIHVLHSKHP-
GDFGA-DAQGAMTKAL-ELFRNDIAAKYKELGFQG-----------------
>myo-pig NP_999401 myoglobin [Sus scrofa].
---------------------------MGL--SDGEWQLVLNV-WGKV--EAD----VAG
HGQ-----EVLIRLFKGHPETLEKF-----DK-FKHLKSEDEMKASEDLKKHGNTVLTAL
GGILKKKGH-HE------AELTPLA-QSHATKH--KIPVKYLEFIS-EAIIQVLQSKHP-
GDFGA-DAQGAMSKAL-ELFRNDMAAKYKELGFQG-----------------
>myo-human NP_976312 myoglobin [Homo sapiens].
---------------------------MGL--SDGEWQLVLNV-WGKV--EAD----IPG
HGQ-----EVLIRLFKGHPETLEKF-----DK-FKHLKSEDEMKASEDLKKHGATVLTAL
GGILKKKGH-HE------AEIKPLA-QSHATKH--KIPVKYLEFIS-ECIIQVLQSKHP-
GDFGA-DAQGAMNKAL-ELFRKDMASNYKELGFQG-----------------
>myo-sp-whale P02185 Myoglobin.
----------------------------VL--SEGEWQLVLHV-WAKV--EAD----VAG
HGQ-----DILIRLFKSHPETLEKF-----DR-FKHLKTEAEMKASEDLKKHGVTVLTAL
GAILKKKGH-HE------AELKPLA-QSHATKH--KIPIKYLEFIS-EAIIHVLHSRHP-
GDFGA-DAQGAMNKAL-ELFRKDIAAKYKELGYQG-----------------
>myo-dolphin P68276 Myoglobin.
----------------------------GL--SDGEWQLVLNV-WGKV--EAD----LAG
HGQ-----DVLIRLFKGHPETLEKF-----DK-FKHLKTEADMKASEDLKKHGNTVLTAL
GAILKKKGH-HD------AELKPLA-QSHATKH--KIPIKYLEFIS-EAIIHVLHSRHP-
AEFGA-DAQGAMNKAL-ELFRKDIAAKYKELGFHG-----------------
>myo-zebrafish NP_956880 myoglobin [Danio rerio].
---------------------------------MADHDLVLKC-WGAV--EAD----YAA
NGG-----EVLNRLFKEYPDTLKLF-----PK-FSGI-SQGDLAGSPAVAAHGATVLKKL
GELLKAKGD-HA------ALLKPLA-NTHANIH--KVALNNFRLIT-EVLVKVMAEKAG-
--LDA-AGQGALRRVM-DAVIGDIDGYYKEIGFA------------------
>myo-tuna P02205 Myoglobin.
----------------------------------ADFDAVLKC-WGPV--EAD----YTT
MGG-----LVLTRLFKEHPETQKLF-----PK-FAGI-AQADIAGNAAISAHGATVLKKL
GELLKAKGS-HA------AILKPLA-NSHATKH--KIPINNFKLIS-EVLVKVMHEKAG-
--LDA-GGQTALRNVM-GIIIADLEANYKELGFSG-----------------
>eye-chicken NM_001008786 Gallus gallus eye-globin (GBE)
---------------------------MSF--SEAEVQSARGA-WEKM--YVD----AED
NGT-----AVLVRMFTEHPDTKSYF-----TH-FKGMDSAEEMKQSDQVRGHGKRVFTAI
NDMVQHLDN-TEAFL---GILNPLG-QKHATQL--KIDPKNFRIIC-DIILQLMEEKFG-
----G-DCKASFEKVT-NEICTHLTNIYKEAGW-------------------
>cyto-zebrafish BC094999 Danio rerio cytoglobin 1
--------------MEGDGGVQLTQSPDSL--TEEDVCVIQDT-WKPV--YAE----RDN
AGV-----AVLVRFFTNFPSAKQYF-----EH-FRELQDPAEMQQNAQLKEHGQRVLNAL
NTLVENLRD-ADKLN---TIFNQMG-KSHALRH--KVDPVYFKILA-GVILEVLVEAFP-
QCFSPAEVQSSWSKLM-GILYWQMNRVYAEVGWENSKK--------------
>cyto-fish3 CAG25613 cytoglobin-1 [Tetraodon nigroviridis].
-----------MERMQRDGEVDHVEQPGPL--TEKEKVMIQDS-WAKV--FQS----CDD
AGV-----AILVRFFVNFPSSKQFF-----KD-FKHMEEPEEMQQSVQLRKHAHRVMTAL
NTLVESLDN-ADRVA---SVLKSVG-RAHALRH--NVDPKYFKILS-GVILEVLGEAFT-
EIITA-EVASAWTKLL-ANMCCGIAAVYKEAGWTELSSSVE-----------
>cyto-fish AJ63523 Tetraodon nigroviridis mRNA for cytoglobin-2 (cygb-2 gene)
MSHREPPPPQLAVQRRDVDGQDGPERAEPL--SDTEREMIRDA-WGHV--YKN----CED
VGV-----SILIRFFVNFPSAKQYF-----SQ-FQDMEEPEEMERSSQLRHHACRVMNAL
NTVVENLHD-PEKVS---SVLAVVG-RAHAVKH--KVEPMYFKILS-GVILEVLCEDFP-
EFFTA-DVQLVWSKLM-ATVYWHVTGAYTDVGWLQVSSSAV-----------
>cyto-xenopus NM_001006869 Xenopus tropicalis cytoglobin (cygb), mRNA
-----------MEKVQGENDMERWERLEEI--TESERGVIKET-WARV--YAN----CED
VGV-----SILIRFFVNFPSAKQHF-----SQ-FKHMEDPLEMEGSVQLRKHARRVMGAV
NSVVENLGD-PEKIT---TVLSIVG-KSHALKH--KVDPVYFKILT-GVMLEVIAEEYA-
KDFTP-DVQLAWNKLR-SHLYSHVLSAYKEAGWTQYPSNSV-----------
>cyto-chicken NM_001008789 Gallus gallus cytoglobin (CYGB)
-----------MEKVQGEMEIERWERSEEI--SDAEKKVIQET-WSRV--YAN----CED
VGV-----SILIRFFVNFPSAKQYF-----SQ-FKHMDDTLEMERSLQLRKHAQRVMGAI
NTVVENLDD-PEKVS---SVLALVG-KAHALKH--KVEPVYFKKLT-GVMLEVIAEAYG-
NDFTP-EAHGAWTKMR-TLIYTHVTAAYKEAGWVSYPSATL-----------
>cyto-human NM_134268 Homo sapiens cytoglobin (CYGB)
-----------MEKVPGEMEIERRERSEEL--SEAERKAVQAM-WARL--YAN----CED
VGV-----AILVRFFVNFPSAKQYF-----SQ-FKHMEDPLEMERSPQLRKHACRVMGAL
NTVVENLHD-PDKVS---SVLALVG-KAHALKH--KVEPVYFKILS-GVILEVVAEEFA-
SDFPP-ETQRAWAKLR-GLIYSHVTAAYKEVGWVQQVPNATTPPATLPSSGP
>cyto-rhesus-p XP_001104888 PREDICTED: similar to cytoglobin [Macaca mulatta
-----------MEKVPGEMEIERRERSEEL--SEAERKAVQAT-WARL--YAN----CED
VGV-----AILVRFFVNFPSAKQYF-----SQ-FKHMEEPLEMERSPQLRKHACRVMGAL
NTVVENLHD-PDKVS---SVLALVG-KAHALKH--KVEPVYFKILS-GVILEVVAEEFA-
NDFPP-ETQRAWAKLR-GLIYSHVTAAYKEVGWVQQVPNATTPPATLPSSGP
>cyto-rat NM_13074 Rattus norvegicus cytoglobin (Cygb)
-----------MEKVPGDMEIERRERNEEL--SEAERKAVQAT-WARL--YAN----CED
VGV-----AILVRFFVNFPSAKQYF-----SQ-FKHMEDPLEMERSPQLRKHACRVMGAL
NTVVENLHD-PDKVS---SVLALVG-KAHALKH--KVEPMYFKILS-GVILDVIAEEFA-
NDFPV-ETQKAWTKLR-GLIYSHVTAAYKEVGWVQQVPNTTTLPATLPSSG-
>cyto-mouse NM_030206 Mus musculus cytoglobin (Cygb), mRNA
-----------MEKVPGDMEIERRERSEEL--SEAERKAVQAT-WARL--YAN----CED
VGV-----AILVRFFVNFPSAKQYF-----SQ-FRHMEDPLEMERSPQLRKHACRVMGAL
NTVVENLHD-PDKVS---SVLALVG-KAHALKH--KVEPMYFKILS-GVILEVIAEEFA-
NDFPV-ETQKAWAKLR-GLIYSHVTAAYKEVGWVQQVPNTTTPPATLPSSGP
>hemo-3-tunicate AJ548502 Ciona intestinalis mRNA for globin (hb3 gene)
---------------------------MSL--TSEQVVLLRSS-WQTI-GKLG----MSN
VGL-----AVLHRLFNDVPETLPFFHSVLSPT---QQTEIEVLKSNAKVVRHASRVGLSI
DKIINLLDN-GEELV---KYLLFLG-QVHVKRS---IPRKYFSAMG-PVLLSVISAVLE-
KDLDA-PVMQAWATAY-GVIEQGIIDGM------------------------
>hemo-1-tunicate AJ548500 Ciona intestinalis mRNA for globin (hb1 gene)
---------------------------MPF--TDEELKLLRDS-WDEV-KKLG----MKE
VGL-----HIFTGLLNAAPSLRTLFYTIDLPD-EEEL-TIDVMRENKKVVAHATRIANAI
SKFIKFLDQ-PDELE---KLLTSLG-ESHARRQ---VDPESFEYVA-PVILSVIGGHLK-
LPSNS-PTLQAWVKAY-GVLRNGIVSAMEA----------------------
>hemo-2-tunicate AJ548501 Ciona intestinalis mRNA for globin (hb2 gene)
---------------------------MGL--TTEEIGLLRSS-WNEM-KTIG----MKE
LGL-----LIFHRLFSDVPRIRKMFYNLELPD-DETL-TMEAMRSNQKMSRHATRIATSI
STYLKLADQ-PEELK---TFLNGLG-ELHAGHN---VEPEDFEYLA-PVMLAVIGGQLN-
LNSNS-SILQAWVKAY-GVLRNGIVRGMYAYQG-------------------
>myo-worm-polychaeta  AAC47259 nerve myoglobin.
--------------------------MAGL--SGADIAVIRST-WAKVQGSGS----ATD
IGR-----SIFIKFFELDPAAQNEF------P-CKGE-SLAALKTNVLLGQHGAKFMEYI
TTAVNGLDDYAGKAH---GPLTELG-SRHKTRG---TTPANFGKAG-EALLAILASVVG-
GDFTP-AAKDAWTKVY-NTISSTMQAAL------------------------
>hemo-IV-polychaeta AAA29162 hemoglobin IV.
---------------------------MGL--SAAQRQVVAST-WKDIAGSDN----GAG
VGK-----ECFTKFLSAHHDIAAVF------G-FSGA-S-D-----PGVADLGAKVLAQI
GVAVSHLGD-EGKMV---AEMKAVG-VRHKGYGYKHIKAEYFEPLG-ASLLSAMEHRIG-
GKMTA-AAKDAWAAAY-ADISGALISGLQS----------------------
>hemo-P3-polychaeta AAA29161 globin P3.
---------------------------MHL--TADQVAALKAS-WPEVSAGDG----GAQ
LGL-----EMFTRYFDENPQMMFVF------G-YSGR-T-SALKHNSKLQNHGKIIVHQI
GQAVSELDD-GSKFE---ATLHKLG-QEHKGFG--DIKGEYFPALG-DALLEAMNSKVH-
G-----LDRTLWAAGY-RVISDALIAGLES----------------------
>hemo-P1-polychaeta CAA37995 globin P1 [Glycera dibranchiata].
---------------------------MHL--TADQVAALKAS-WPEVSAGDG----GAQ
LGL-----EMFTKYFHENPQMMFIF------G-YSGR-T-EALKHSSKLQHHGKVIIDQI
GKAVAEMDN-AKQMA---GTLHALG-VRHKGFG--DIRAEFFPALG-MCLLDAMEEKVP-
G-----LNRTLWAAAY-REISDACIAGLQS----------------------
>hemo-P2-polychaeta AAA29160 globin P2.
---------------------------MPL--TADQVAALKAS-WPEVSAGDG----GGQ
LGL-----ELFTKYFHENPQMMFIF------G-YSGR-T-DALKHNAKLQNHGKVIIDQI
GKAVAEMDN-AKQMA---GTLHALG-VRHKGFG--DIRADFFPALG-MCLLDAMEEKVP-
G-----LNRTLWAAAY-REISDALVAGLES----------------------
