>hisF-Pseudomonas1 [Pseudomonas aeruginosa] (Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas; aeruginosa)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MVRRRVIPCLLL--
--KDRG--LVKTVKF--------KEPKYVGDPINAIRIFNEKEVDELILLDIDA---SRL
NQEPNYELIAEVAGECFMPICYGGGIKTLEH-----------AEKIFSLGVEKVSINTAA
LMDLS-------------LIRRIADKFGSQSVVGSIDCRKGF------------------
-----WGGHSVFSENG----TRDMKRSPLEWAQALEEAGVGEIFLNSIDRDGVQKGFDNA
LVENIASNVHVPVIACGGAGSIADLIDLFERTCVSAVAAGSLFVFHGKHRAVLISYPDVN
KLDVG--------
>hisF-Campylobacter1 [Campylobacter jejuni] (Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Campylobacteraceae; Campylobacter; jejuni)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLKTRIIPCVLL--
--KNSQ--LVKSIEF--------KDFRTIGHLTSTMRIYNARNVDELIILDIDA---SKS
G-EIDFESIEDLAKECFMPLTIGGGIKTLED-----------IQKILNLGADKISINSKA
LEDMD-------------FISKAGNRFGSQCIVCSIDVKRKG------------------
------DQFCVYDRGN------LLEKSPLELALEYEKKGAGELLLTSVDFEGKAKGYDLE
LLKIFQNKLKIPLIINGGLSKPSDGVEALNLG-ADALAGAYIFHFSKYTPKDVKEELARQ
GFAVRLL------
>hisF-Schizosaccharomyces [Schizosaccharomyces pombe] (Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces; pombe)
MIVSIVDYGSGNVRSLINAVRYLGFETQWIRNPHDIEKAECLIFPGVGNFGFVCDSLAKQ
GFLEPLRRYALSGKPFMAVCVGIQALFEGSVEAPHSKGLGVFPGLVQRFDNDDKTVPHIG
WNSCAVRSDTSKEFFGMRPHDKFYFVHSYMIPEKGLILPPEFKIATTKYGNETFVGAIVK
NNFLATQFHPEKSGSAGLRCLKAFLTGNYEQPISGEASKLIENSFGGLTKRIIACLDVRS
N-DAGDLVVTKGDQYDVREKSSGSEVRNLGKPVELCQRYFQEGADEVVFLNITSFRNCPM
ADAPMLQVLEKAAQTVFVPLTVGGGIRDVSDPDGTFHPAVEVAGIYFRSGADKVSIGSDA
VYAAEKYYENGKKLSGKTAIETISKAYGNQAVVISVDPKRQYVKVPEDTKHHVVKTSRLG
PNGEAYCWYQCTVKGG----REYRDIDVVELTRACEAMGAGEVLLNCMDQDGSNAGYDIE
LVRLVKNSVNIPVIASSGAGIPQHFEEVFKETDCDAALAAGIFHRQTCRIEDVKEYLAIH
DVLVRT-------
>hisF-Xylella [Xylella fastidiosa] (Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales; Xanthomonadaceae; Xylella; fastidiosa)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLSRRLIPCLDV--
--RDGR--VVKGVKF--------RDHVDMGDIVELALRYRDHGADELVFYDIGA---SPR
GRSVDYRWVERVARLIDIPFCVAGGIGQVET-----------ARAVLHAGADKISINSPA
LRQPA-------------LISALAEAFGVQCVVVGIDSIREA------------------
-----DGQWRVRCNTGDPDKTQALPLRTLDWIVEAQRLGAGEIVLNCMDSDGVRCGYDIA
QLSQARALCQVPLVASGGAGNMQHFADVFHKADVDGALAASVFHSGAILIPGLKQFLREQ
QIEVRDV------
>hisF-Buchnera [Buchnera aphidicola (Acyrthosiphon pisum)] (Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera; aphidicola)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLAKRIIACLDV--
--DDGV--VVKGIKF--------QNHKIVGDIVPLARRYAKEGIDELVFYDITA---ATK
NKLVDRSWIKNVSKVINIPFCVAGGIKSVED-----------AKKVLSSGADKISINSSA
LIDPN-------------LITKISERFGVQCVVIGIDSWFDK------------------
----TKNSYMVQQYTGDISKTYQTSWKTSDWVKKVQEKGAGEIVLNMMNKDGLQKGYDIS
HLSEIRKICKVPLIASGGAGSVEHFYEALYYSNVDGVLAASVFHKNIVEIKVLKKKLIAR
GMEIREC------
>hisF-Campylobacter2 [Campylobacter jejuni] (Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Campylobacteraceae; Campylobacter; jejuni)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLTKRIIACLDV--
--KDGR--VVKGTQF--------KNHKDMGDIIELARYYSQNGIDELVFYDIAA---SAR
KERISREWVSEVAKNINISFCVAGGIKSEED-----------AAELLANGADKISINSPA
LNDPS-------------LITRLAKSFGVQCVVVGIDSFKDE------------------
-----NGNLKVFQYTGDEKTSKHSGKSTLEWVKKVQDLGAGEIVLNMMNQDGVKNGYDLE
QLEAVYKICKVPLIASGGAGKMEHFLEAFKLG-IDGALAASVFHQKLIDIKELKIYLKNQ
GLSIRI-------
>hisF-Haemophilus [Haemophilus influenzae] (Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Haemophilus; influenzae)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLAKRIIPCLDV--
--RDGQ--VVKGVQF--------RNHEIIGDIVPLAQRYAQEGADELVFYDITA---SSD
GRTVDKSWVERIAQVIDIPFCVAGGIKTIED-----------AEKLFAFGADKISINSPA
LADPT-------------LISRLADRFGVQAIVVGIDSWFEQ------------------
----ETGKYWVNQYTGDETRTRQTHWQLLDWVKEVQQCGAGEIVLNMMNQDGLRNGYDLA
QLKLVRGVCRVPLIASGGAGKMVHFRDAFIEAKVDGALAASVFHKQIIEIGELKSYLVQS
AIEIRSE------
>hisF-Pasteurella [Pasteurella multocida] (Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Pasteurella; multocida)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLAKRIIPCLDV--
--RDGQ--VVKGVQF--------RNHEIIGDIVPLAQRYAEEGADELVFYDITA---SSD
GRTIDKSWVERVAQVIDIPFCVAGGIKSVED-----------AEKLFAFGADKISINSPA
LADPD-------------LINRLADRFGVQAIVVGIDSWFEK------------------
----ETGKYWVNQYTGDESRTRQTHWQLLDWVKEVQQRGAGEIVLNMMNQDGVRQGYDIA
QLKLVRNLCHIPLIASGGAGEMVHFRDAFIEANVDGALAASVFHKRIIDIGELKDYLRKE
KIKIR--------
>hisF-Vibrio [Vibrio cholerae] (Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; cholerae)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLAKRIIPCLDV--
--RDGQ--VVKGVQF--------RNHEIIGDIVPLAKRYAEEGADELVFYDITA---SSD
GRVVDKSWVARVAEVIDIPFCVAGGIKSAQD-----------AARILEFGADKVSINSPA
LANPQ-------------LITDLADRFGVQCIVVGIDSYFDK------------------
----ETGQYQVYQFTGDESRTRATQWQTCDWVQEVQKRGAGEIVLNMMNQDGVRNGYDLE
QLNLVRSVCRVPLIASGGAGAMEHFAQAFTQANVDGALAASVFHKQIINIGELKQYLKQQ
GIEVRR-------
>hisF-Yersinia [Yersinia pestis] (Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Yersinia; pestis)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLAKRIIPCLDV--
--KDGQ--VVKGVQF--------RNHEIIGDIVPLAQRYAQEGADELVFYDITA---SSD
GRVVDKSWVARVAEVIDIPFCVAGGIKSVED-----------ASQILTFGADKISINSPA
LADPT-------------LITRLADRYGVQCIVVGIDTWYDT------------------
----ESDSYQVYQFTGDEKRTKATTWQTEDWVKEVQLRGAGEIVLNMMNQDGVRNGYDLR
QLQQMRAICHVPLIASGGAGTPDHFLEAFRDADVDGALAASVFHKQIINIGELKKYLSEQ
GVEIRVC------
>hisF-Escherichia [Escherichia coli] (Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia; coli)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLAKRIIPCLDV--
--RDGQ--VVKGVQF--------RNHEIIGDIVPLAKRYAEEGADELVFYDITA---SSD
GRVVDKSWVSRVAEVIDIPFCVAGGIKSLED-----------AAKILSFGADKISINSPA
LADPT-------------LITRLADRFGVQCIVVGIDTWYDA------------------
----ETGKYHVNQYTGDESRTRVTQWETLDWVQEVQKRGAGEIVLNMMNQDGVRNGYDLE
QLKKVREVCHVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLATQ
GVEIRIC------
>hisF-Salmonella [Salmonella typhimurium] (Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella; typhimurium)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLAKRIIPCLDV--
--RDGQ--VVKGVQF--------RNHEIIGDIVPLAKRYADEGADELVFYDITA---SSD
GRVVDKSWVARVAEVIDIPFCVAGGIRSIDD-----------AAKILSFGADKISINSPA
LADPT-------------LITRLADRFGVQCIVVGIDTWFDD------------------
----ATGKYHVNQYTGDENRTRVTQWETLDWVQEVQQRGAGEIVLNMMNQDGVRNGYDLT
QLKKVRDVCRVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLAGQ
GVEIRIC------
>hisF-Staphylococcus [Staphylococcus aureus subsp. aureus Mu50] (Bacteria; Firmicutes; Bacillales; Staphylococcus; aureus)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MIKKRIIPCLDV--
--KDGR--VVKGIQF--------KGLRDIGNPVDLAIYYNEAGADELVFLDISK---TEE
GHSLMLEVIEQTASRLFIPLTVGGGIQSLDD-----------ITQLLNHGADKVSLNSSA
LKNPQ-------------LIKQASDKFGRQCICIAIDSYYDP------------------
----ERKAHYCCTHGG----KKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGMKQGFDIE
HLAKIKSLVNIPIIASGGGGNAQHFVELFNQTDVSAGLAASILHDRETTVQSIKEVIRQG
GIAVR--------
>hisF-Halobacterium [Halobacterium salinarum] (Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium; salinarum)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MTLTKRVIPCIDVDL
D-DDGEPAVYTGVNF--------EELAYTGDPVEMAKRYNEAGADEFVFLDITA---SAE
GRETMLDTVSAVADEVFIPLTVGGGIRDTDD-----------IRETLRAGADKVSINSGA
IADPS-------------LVDRGAKAFGSQCIVISVDARRRF------DEQGQHYTQ---
-VDGESCWFECTVHGG----REGTGMDAIEWVQEAQRRGAGELFVNSIDADGTQDGYDVP
LTAAVCDAVSTPVIASSGCGAPGDMADAYDAG-ADAALAASIFHFDEYSIAETKETLADA
GYPIRAPDA----
>hisF-Deinococcus [Deinococcus radiodurans R1] (Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae; Deinococcus; radiodurans)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MLRGVLAKRIVPCLDV--
--QNGR--VVKNVRF-------FEDHRDAGDPLVLAQAYEAQQADELVFYDITA---THE
GRSLMLDVAARVAEQVMMPLTVGGGVGALSD-----------FRQLLLAGADKISVNSGA
VKRPE-------------LIREASDHYGAQCVMLSIDAKRRP------------------
----GGQGWTVHIGGG----RVDTGLDLLAWARRGQELGAGELCLNVMDADGTRAGFDLE
ATRAVAREVDLPVIASGGAGKVQDFYDVLTAGEADAALAASVFHFGELTVPQVKTSLAAQ
GVPVRPEWRGATE
>hisF-Lactococcus [Lactococcus lactis subsp. lactis] (Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Lactococcus; lactis)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLTKRIIPCLDI--
--KNGK--VVKGINF--------VSLREIGDSVELAKIYEEQCADEIVFLDITA---SFE
EREIIGELIGRAARELSIPLTFGGGIRSIDD-----------FRRILARGADKVSVNSAA
IENPE-------------LIRQAANELGVQCVVVAIDAKKRA------------------
----DHRGYDVYIKGG----RENAGLDLVDWAKKCERLGAGEILLTSMDKDGTKTGYDLE
MLNDVCTAVNIPVVASGGCGKISDIVEVFQNTRSDAALVASLFHYGEATVDEVKDELIKN
NIPARIIKKETL-
>hisF-Sulfolobus [Sulfolobus solfataricus] (Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; solfataricus)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MTTKRIIACLDV--
--KDGN--VVKGVNF--------LNLQLKGDPVSLASLYEEEGADEIVFLDITA---TIE
ARKALYNVIKDTASVLSIPLTVGGGIRTPDD-----------VSMALRSGADKVSINTAA
VESSQ-------------IVKKSAEEFGSQAVVVAIDVKKVS------------------
------GNWIVFTKSG----TYNTRLDAIKWAKKVEELGAGEILLTSIDRDGTRLGYDLE
LTRKIVDSVNIPVIASGGAGKMEHFYEVFSLAKADAALAAGIFHDGIIKIKDLKSYLSQK
GIEVRM-------
>hisF-Corynebacterium [Corynebacterium glutamicum] (Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Corynebacteriaceae; Corynebacterium; glutamicum)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MGVAIRVIPCLDV--
--DNGR--VVKGVNF--------ENLRDAGDPVELAKRYDEEGADELTFLDVTA---SKH
GRGTMLDVVRRTADQVFIPLTVGGGVRSEED-----------VDQLLRAGADKVSVNTSA
IARPE-------------LLSELSKRFGAQCIVLSVDARRVP-------------EG---
-GTPQPSGFEVTTHGG----SKSAELDAIEWAKRGEELGVGEILLNSMDGDGTKNGFDLE
LLEKVRAAVSIPVIASGGAGKAEHFPPAVAAG-ANAVLAATIFHFREVTIAEVKGAIKDA
GFEVRK-------
>hisF-Mycobacterium1 [Mycobacterium leprae] (Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium; leprae)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MYSGNGLAVRVIPCLDV--
--YCGR--VVKGVNF--------KNLRDAGDLVELAAAYDAEGADELAFLDVTA---SSS
GRATMLEVVRCTAEQVFIPLMVGGGVRTVAD-----------VDVLLRAGADKVAVNTAA
IARPE-------------LLADMAGQFGSQCIVLSVDARTVP-------------TG---
-SARTPSGWEATTHGG----YRGTGIDAVEWAARGADLGVGEILLNSMDADGTKAGFDLA
MLRAVRAAVTVPVIASGGAGAIEHFVPAVTAG-ADAVLAASVFHFRELTIGQVKDAMAAA
GIAVR--------
>hisF-Mycobacterium2 [Mycobacterium tuberculosis] (Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium; tuberculosis)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MYADRDLPGAGGLAVRVIPCLDV--
--DDGR--VVKGVNF--------ENLRDAGDPVELAAVYDAEGADELTFLDVTA---SSS
GRATMLEVVRRTAEQVFIPLTVGGGVRTVAD-----------VDSLLRAGADKVAVNTAA
IACPD-------------LLADMARQFGSQCIVLSVDARTVP-------------VG---
-SAPTPSGWEVTTHGG----RRGTGMDAVQWAARGADLGVGEILLNSMDADGTKAGFDLA
LLRAVRAAVTVPVIASGGAGAVEHFAPAVAAG-ADAVLAASVFHFRELTIGQVKAALAAE
GITVR--------
>hisF-Methanothermobacter [Methanothermobacter thermautotrophicus str. Delta H] (Archaea; Euryarchaeota; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanothermobacter; thermautot.)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MSSGLFQMRRNMFYVDSDTSELLMAIEMLAKRIIPCLDCDL
QVPNGR--VVKGVEF--------KQIRYAGDPVELATRYYEDGADEIVFLDITA---SHE
RRETMTHVIEATTENVFVPICVGGGIRKPED-----------YFKMLKAGADKCSTNTAA
IKNPE-------------LINEASDLVGSQACVVAIDAKRRY-IENPRESDERFIIE---
-VDDGYCWYECSIYGG----REFTGIDAVKWAMECQDRGAGEILLTSMDRDGTKMGYDIP
LTRTMSENLDIPVIASGGVGEPEHIYEAFTDGKADAALAASIFHFNEYPVPAVKEYLRSR
GVPIRL-------
>hisF-Pyrobaculum [Pyrobaculum aerophilum] (Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae; Pyrobaculum; aerophilum)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MDVALRIIPCLDI--
DGKAGV--VVKGVNF--------QGIREVGDPVEMAVRYEEEGADEIAILDITA---APE
GRATFIDSVKRVAEAVSIPVLVGGGVRSLED-----------ATTLFRAGADKVSVNTAA
VRNPQ-------------LVALLAREFGSQSTVVAIDAKWNG------------------
------EYYEVYVKGG----REATGLDAVKWAKEVEELGAGEILLTSIDRDGTGLGYDVE
LIRRVADSVRIPVIASGGAGRVEHFYEAAAAG-ADAVLAASLFHFRVLSIAQVKRYLKER
GVEVRI-------
>hisF-Nostoc [Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120)] (Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc; sp.)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLSKRILPCLDV--
--KAGR--VVKGVNF--------VDLKDAGDPVELAKVYNDAGADELVFLDITA---THE
DRDTIIDVVYRTAEQVFIPLTVGGGIQSLEN-----------VKALLRAGADKVSINSAA
VRDPE-------------LIDRASDHFGNQCIVVAIDARRRV------------------
--DPSNPGWDVYVRGG----RENTGLDALSWAKEVEKRGAGELLVTSMDADGTQAGYDIE
LTRAIAESVEIPVVASGGAGNCEHIYTALTEGKAEAALLASLLHYGQLSVAEIKNYLHES
QVPVRLYTQF---
>hisF-Synechocystis [Synechocystis sp. PCC 6803] (Bacteria; Cyanobacteria; Chroococcales; Synechocystis; sp.)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MTLAKRILPCLDV--
--NAGR--VVKGINF--------VDLQDAGDPVELARAYNEAGADELVFLDITA---THE
QRDTIIDVVYRTAEEVFIPLTVGGGISTLEH-----------IKNLLRAGADKVSVNSSA
VRDPD-------------FISRASDRFGRQCIVVAIDARRRL------------------
--DADNPGWDVYVRGG----RENTGLDAIAWAEEVAKRGAGELLVTSMDGDGTQAGYDLA
LTAAIAERVEIPVIASGGAGNCQHVYEAFTEGKAEAALLASLLHYGQLTIGELKTFLEAR
QIPVRHTAVCG--
>hisF-Methanopyrus [Methanopyrus kandleri] (Archaea; Euryarchaeota; Methanopyri; Methanopyrales; Methanopyraceae; Methanopyrus; kandleri)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MALAKRIIPCLDV--
--KDGR--VVKGVRF--------RGLRDAGDPAELAHHYYRHGADEIVFLDISA---SPE
GRRLMVDVVRRTAEKVFIPMTVGGGISDVED-----------FRRALTAGADKVSVNTAA
VENPE-------------LISEAADIFGSQCVVVAIDAKREP-LKPEHEHVADHIFS---
-NDDGEYWFRVYVRGG----REPVDLDAITWAKRVEELGAGEILLTSIDADGTQEGYDIE
LTREVCNAVSIPVIASGGCGHPKHMVEVFKEADADAALAASIFHYGKFTIEEVKEHLAER
GVRVRQC------
>hisF-Neisseria1 [Neisseria meningitidis serogroup A] (Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Neisseria; meningitidis)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MALAKRIIPCLDV--
--KDGR--VVKGVNF--------IGLRDAGDPVEAAKRYNGEGADELTFLDITA---SSD
NRDTILHIIEEVAGQVFIPLTVGGGVRTVAD-----------IRRLLNAGADKVSINTAA
VTRPD-------------LIDEAAGFFGSQAIVAAVDAKAVN------------------
---PENTRWEIFTHGG----RNPTGLDAVEWAIEMQKRGAGEILLTGMDRDGTKQGFNLP
LTRAVAEAVDIPVIASGGVGNVRHLIEGITEGKADAVLAAGVFHFGEIAIREAKHAMREA
GIEVRL-------
>hisF-Neisseria2 [Neisseria meningitidis serogroup B] (Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Neisseria; meningitidis)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MALAKRIIPCLDV--
--KDGR--VVKGVNF--------IGLRDAGDPVEAAKRYNGEGADELTFLDITA---SSD
NRDTILHIIEEVAGQVFIPLTVGGGVRTVAD-----------IRRLLNAGADKVSINTAA
VTRPD-------------LIDEAAGFFGSQAIVAAVDAKAAN------------------
---PENTRWEIFTHGG----RNPTGLDAVEWAVEMQKRGAGEILLTGMDRDGTKQGFNLP
LTRAVAEAVDIPVIASGGVGNVRHLIEGITEGKADAVLAAGIFHFGEIAIREAKRAMREA
GIEVRL-------
>hisF-Pseudomonas2 [Pseudomonas aeruginosa] (Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas; aeruginosa)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MALAKRIIPCLDV--
--DNGR--VVKGVKF--------ENIRDAGDPVEIARRYDEQGADEITFLDITA---SVD
GRDTTLHTVERMASQVFIPLTVGGGVRSVQD-----------IRNLLNAGADKVSINTAA
VFNPE-------------FVGEAADRFGSQCIVVAIDAKKVS------------------
-APGEAPRWEIFTHGG----RKPTGLDAVLWAKKMEDLGAGEILLTSMDQDGVKSGYDLG
VTRAISEAVNVPVIASGGVGNLEHLAAGILEGKADAVLAASIFHFGEYTVPEAKAYLASR
GIVVR--------
>hisF-Ralstonia [Ralstonia solanacearum] (Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Ralstonia; solanacearum)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLAKRIIPCLDV--
--TNGR--VVKGVNF--------VELRDAGDPVEIARRYDEQGADEITFLDITA---TSD
GRDLILHIIEAVASQVFIPLTVGGGVRALED-----------VRRLLNAGADKISMNSSA
VANPQ-------------LVSDASARHGAQCIVVAIDAKKVS------------------
-ADGEPPRWEVFTHGG----RKATGLDAVAWAREMARRGAGEILLTSMDRDGTKSGFDLE
LTRAVSDAVPVPVIASGGVGNLQHLADGIKLGHADAVLAASIFHYGEHTVGEAKRFMAQQ
DIPVRM-------
>hisF-Caulobacter [Caulobacter vibrioides (Caulobacter crescentus)] (Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales; Caulobacteraceae; Caulobacter; vibrioides)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLKTRIIPCLDV--
--KDGR--VVKGVNF--------VSLRDAGDPVEQARAYDAAGADELMFLDITA---SSE
GRGLILDVISRTAEVCFMPVSVGGGVRQVSD-----------MRRLLLAGADKVSVNTAA
VENPD-------------LIAGGADAFGSQCVVVAIDAKARE------------------
----DGSGWNVWTYGG----RKDTGIDVVEWAAKVVERGAGEILLTSMDRDGAKIGYDIP
LLQAVTGAVNVPVIASGGAGKTEHLIEAAREGHAAAVLAASIFHFGEISIGEAKQAMADA
GIPVRLDALKGAA
>hisF-Agrobacterium [Agrobacterium tumefaciens str. C58] (Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium; tumefaciens)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MTLKARIIPCLDV--
--KDGR--VVKGVNF--------VDLIDAGDPVEAAKAYDAAGADELCFLDITA---SSD
NRDTIFDVVSRTADHCFMPVTVGGGVRSVAD-----------IRKLLLCGADKVSINSAA
VKDPD-------------FVAQAADKFGNQCIVVSIDAKRVS------------------
-KDGEADRWEIFTHGG----RQPTGIDAVEFAIKMVERGAGELLVTSMDRDGTKSGYDIG
LTRSIADQVRVPVIASGGVGTLDDLVAGVRDGHATAVLAASIFHFGTYSIGEAKSYMAEH
GIAMRLD------
>hisF-Mesorhizobium [Mesorhizobium loti] (Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Phyllobacteriaceae; Mesorhizobium; loti)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLKARVIPCLDV--
--KDGR--VVKGVNF--------VDLIDAGDPVEAAKAYDAAGADELCFLDITA---SSD
NRETIFDVIARTAEQCFMPLTVGGGVRQVAD-----------IRKLLLAGADKVSINTAA
VKNPD-------------FVAEAADKFGNQCIVVAIDAKKVS------------------
-GAGEADRWEIFTHGG----REKTGIDAVEFARKMVDRGAGEILLTSMDRDGTKAGYDIA
LTRAIADAVRAPIIASGGVGTLDHLVEGIRDGHAGAVLAASIFHFGTYTIAQAKAHMAAA
GLPMRLDSSGDRP
>hisF-Brucella [Brucella melitensis] (Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Brucellaceae; Brucella; melitensis)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MTLKARVIPCLDV--
--KDGR--VVKGVNF--------VDLIDAGDPVEAARAYDAAGADELCFLDITA---SSD
NRETIFDVVARTAEQCFMPLTVGGGVRQVAD-----------IRKLLLAGADKVSINTAA
VKNPE-------------FVAEAADKFGNQCIVVAIDAKKVS------------------
-GAGENDHWEIFTHGG----RQPTGIDAVEFAQKVVDLGAGEILLTSMDRDGTKAGYDVA
LTRAVADSVRAPVIASGGVGTLDHLVAGIRDGHATAVLAASIFHFGTYTIGEAKRYMAEA
GIPMRLDPVR---
>hisF-Sinorhizobium [Sinorhizobium meliloti (Rhizobium meliloti)] (Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium; meliloti)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MTLKARVIPCLDV--
--KDGR--VVKGVNF--------VDLIDAGDPVEAARAYDAAGADELCFLDITA---SSD
NRETIFDVVARTAEQCFMPLTVGGGVRQVAD-----------IRKLLLAGADKVSINTAA
VKNPE-------------FVAEAADKFGDQCIVVAIDAKKVS------------------
-AQGEADRWEIFTHGG----RQPTGIDAIEFARKVVDLGAGEILLTSMDRDGTKSGYDIS
LTRAIADAVRAPVIASGGVGTLDHMVEGIRDGHATAVLAASIFHFGTYSIGEAKRHMAKH
GIAMRLD------
>hisF-Bacillus1 [Bacillus halodurans] (Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; halodurans)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLTKRIIPCLDV--
--KDGR--VVKGVQF--------VDLRDAGDPVELAAFYDEQGADELVFLDISA---SHE
GRETMIDVVEKVAGTLAIPFTVGGGINSLED-----------MKRVLRAGADKVSLNTAA
VTRPE-------------LITEGADYFGSQCIVVAIDAKYDE------------------
----ALGSWRIYTHGG----RTPTEWEVCDWAREAVRRGAGEILLTSMDQDGAKTGFDLA
LTTKVSEAVSVPVIASGGAGAKEDFVDVFMNAYADAALAASIFHYKETSVAEVKTHLREE
GVAVR--------
>hisF-Bacillus2 [Bacillus subtilis] (Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; subtilis)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MITKRIIPCLDV--
--KEGR--VVKGIQF--------LELKDAGDPVELAEVYDREGADELVFLDISA---SHE
GRKTMVDVVEQVAAKLAIPFTVGGGINQLSD-----------MKTILRAGADKVSVNTAA
VLRPE-------------LITEGAEFFGSQCIVLAIDAKYDK------------------
----ESDTYKVYTHGG----RKKTDWEVTAWAKEGVKRGAGEILLTSMDSDGEKKGFDHT
LTKLVSEAVPVPVIASGGAGNAQHMLEAFTKGEADAALAASIFHYKETSIKEVKSYLKEY
GVNVR--------
>hisF-Clostridium [Clostridium acetobutylicum] (Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium; acetobutylicum)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLTKRIIPCLDV--
--DMGR--VVKGVNF--------VNLKDVGDPVEIADFYNREGADEIVFLDISA---TNE
GRNTMIDVVRRTAEKVFIPLTVGGGIRDVDD-----------FKNILRAGADKISINSAA
IRNPE-------------LINEAAKKFGSQCVVVAVDARRNI------------------
----ETGGFNVFINGG----RVDTSLDAIEWVKKCESLGAGEILLTSMDADGTKNGYDVE
LTGAVCDAVRIPVIASGGCGRLEDFDEIFKKTSADAALVASLFHYKEYTVGEVKNYLREN
SIQVRL-------
>hisF-Listeria [Listeria innocua] (Bacteria; Firmicutes; Bacillales; Listeriaceae; Listeria; innocua)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLTKRIIPCLDV--
--TAGR--VVKGVNF--------VSLTDVGDPVEIAKAYNEAGADELVFLDITA---TVE
LRQTMIDVVERTAEQVFIPLTVGGGINSVND-----------MKELLQAGADKISLNSAA
IKRPE-------------LIQEGANKFGNQCIVVAIDAKWNG------------------
------SNWHVFTRGG----RDDTGLDAIEWAKKATQLGAGEILLTSMDGDGTKNGYDIP
LTKAISEAVSVPVIASGGCGNASHMVEVFEQTNATAALAASIFHYGELSIKNVKTTLLEK
GVNIRP-------
>hisF-Methanocaldococcus [Methanocaldococcus jannaschii] (Archaea; Euryarchaeota; Methanococci; Methanococcales; Methanocaldococcaceae; Methanocaldococcus; jannaschii)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLTKRIIPCLDI--
--KDGR--VVKGTKF--------LNLRDAGDPVELAQYYDDEGADELVFLDITA---SAE
KRDIIIDVVERTAEKVFIPLTVGGGIKSIED-----------FRRILRAGADKVSINTAA
VKNPN-------------LIKEASEIFGSQCVVVAIDAKRHYVNEDEIDKINKNVVK---
-VEDGYCWFEVYIYGG----RKETGIDAINWAKKVEELGAGEILLTSIDKDGTKSGYDLI
LTKEISKSVKLPVIASGGCGKPEHVYEAFVYGKADAALMAGILHYREYTIEEIKKYCADR
GIPMRLL------
>hisF-Aquifex [Aquifex aeolicus] (Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex; aeolicus)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLAKRIIPCLDV--
--DKGR--VVKGVKF--------LNLRDAGDPVEVAKRYEEEGADELVFLDITA---SAE
DREIMIDVVKKVAETVFMPFTVGGGIRSLED-----------MRRLLEAGADKISINTAA
VKNPN-------------LIYEGAKRFGSQCIVVAIDAKRKG------------------
------NSWEVYIHGG----RTPTGLDAVEWAKKVESLGAGEILLTSMDRDGTKDGYDIE
LNRAISEAVNIPVIASGGAGKKEHFYEVFSKTKVEAALAASVFHFREISIPELKEYLLER
GINVRPLD-----
>hisF-Archaeoglobus [Archaeoglobus fulgidus] (Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae; Archaeoglobus; fulgidus)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLAKRIIPCLDVTL
DESEAR--VVKGVEF--------VNLRDAGDPVELAKRYDEEGADELVFLDITA---SPE
GRRTMIDVIERTAEQVFIPFTVGGGIKSIED-----------INTILSAGADKVSINTAA
VKNPE-------------FVREAADIFGSQCIVVAIDCRRNF----DLSKGEYIVEL---
-EDGTKAWYEVVIYGG----RKPVGIDAVWWAKRVEELGAGEILLTSMNRDGTKDGFDIP
ITRKISEEVNIPVIASGGAGTKEHFYEGFVEGKADACLAASIFHYREIGIREIKEYLAER
GVQVRL-------
>hisF-Methanosarcina [Methanosarcina acetivorans] (Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; acetivorans)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLTKRIIPCLDVTL
DRAGGC--VVKGVEF--------VDLKEAGDPVELAKRYNEDGADELVFLDITA---SAH
GRETMIDVIERTADEVFIPLTVGGGISSIDA-----------IRQILRAGADKVSVNTSA
VKNPD-------------FIKESSDIFGAQCIVTAIDCRRNT--DIKNNPDKTVLEL---
-EDGTPAWYEVVIYGG----REATGIDAVQWAKKAEELGSGEILLTSMDRDGTCAGYDLP
ITRKLSEELDIPIIASGGVGNPQHIYEGFSEGKADAALAASIFHFSEYSIWEVKEYLRER
EIPVRL-------
