>Trichomonas [Trichomonas vaginalis G3] (Eukaryota; Parabasalidea; Trichomonada; Trichomonadida; Trichomonadidae; Trichomonadinae; Trichomonas; vaginalis)
------------------XNAEHDAIVKECIAEAAKSEDPIGTLSVLLKKKAPKALIEKV
VGREVLDSRGNPTVEVDVYVKYLGRITLAGRSSAPSGASTGVGEALELRDGDKARYGGKG
TQKAAKNVTEVLSPALKG--MCFCDFPALDKKIC-DTDGTVL-----K--KNVGGNACTA
TSFALAEAGAAIQEIELFQYLAKAFYGGCDKVPK-------KFKLPSPFFNILNGGKHAG
-GNLKFQEFMVTPTRKVPFPDQLRMIAEVYQKLGGILVKKYGLSAKNLGDEGGFAPNLDS
PEEALVVIEEAIKAAGYEAG--------KD--VFIAMDVASSEFY-DEEKKLYEVE----
-----VGKFLNADQMIEYYEDL---LKRHPAIVSIEDALGELDYENWTKLNAKI---GDK
VQLVGDDLYTTNPITIKKGLEGKWCNALLLKVNQIGTISEGMEAARLILNAGHRVMVSHR
SGETCNSVIADLAVAIGAQAIKTGSTARGERIQKYTRLLQIYDYL-------KEHDMLAE
E--------------
>Spironucleus [Spironucleus vortens] (Eukaryota; Diplomonadida; Hexamitidae; Hexamitinae; Spironucleus; vortens)
------------------------------------------------------------
---------------------------------------------LELRDGG-ADYAGKG
VEKALNNIRTIIAPALIG--MDVTNQVAIDKKLE-EIDGTEN-----KTFKKIGANAALP
VSMACCVAAAAFKKMPLWKYI-----SEISGQ---------SPSLPVPCLNIINGGKHAG
-NMLAPQEYMVAPYKATSMHEAMKWGMEVYACLQKGLKKTFGIGSTAVGDEGGFAPQVND
PEEPLKLIMQAITDAKLE----------GK--IGICMDVAASEFF-CEKEKKYNLKFKNT
DG---QTNWKTGAEMVDLYMSF---IQKYP-IVSIEDPFDQDDFESYALLLQKIKAGNHK
TQVVGDDLTVSQVSRVQMAIDKKACNALLLKVNQVGTVMGAINAAKLAFSDKWHTMVSHR
SGETEDVFISHLVVGLGTMQI---------------------------------------
---------------
>Giardia [Giardia lamblia ATCC 50803 (Giardia intestinalis ATCC 50803)] (Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; lamblia)
--------------------------------------------------XEAPSTIKAI
KARMIIDSRGTPTTEVELTTQ-LG---V-FRAACPSGASTGMHEALELRDKDPSAFRGKG
VEQALENIRKIIAPALIG--MPVRDQRAIDEKLQ-ELDGTAG-----KTFSILGANAVLP
VSMACCLAAAREEHISLYQYL-----NRLANSNSSNVTGARDVRLPVPCMNIINGGKHAG
-NKLGPQEYMIAPTKAKNFMQAMQMGCEVYSKLKEILKDEFGLAATAVGDEGGFAPNVAD
PEVPLKYITKAIDACGYN----------GL--MGICIDAAASEFY-SKNENVYDLNFKDP
E----NPNKVSGAELANIYLGW---CRRYP-IVSFEDPFDEEDHTTFANFLAALRQEGLP
TQVVGDDLTVSQVSHIQKAETYKSCSALLLKINQVGTITGAIDAANLAMSYGWSVMVSHR
SGETEDVFIAHLATALGCGQIKSGAPSRSERCAKYNELLRIEDST---------KIPYGF
EAWK-----------
>Aeropyrum [Aeropyrum pernix K1] (Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales; Desulfurococcaceae; Aeropyrum; pernix)
-------------------------------------------------XGVNDFAIERV
WGLQVLDSRGNPTVKAYVKLA-GG---SLGWGIAPSGASRGEREAVELRDGG-GKWRGKG
VSRAVSLLNTVVAPRLEG--VDARRQAQIDRLLI-ELDGTPN-----K--SRLGGNTTTA
LSIAVSRAAAAQARLELFQYL-----GGAG-----------ARRLPIPLLNVINGGVHAG
-NELDFQEFMIIPYGFESFTEAMRAAVETYGELKSLLKDRYGASAVNVGDEGGFAPPMRS
AEEALKTLVDAVEKAGYQPG--------SE--IALGIDAAASQLY---SNGRYSV-----
-----EGKSLSREELLSLYQRL---VEQYP-IVYLEDPFSEDDYEGFKAAVDAL---STE
TIIVGDDLLVTNPQRVKEASALKAVTGLLVKVNQVGTLTEALEAIQAARDRGIVHIVSHR
SGDTEDTFIADLAVATEALMIKTGAPARGERTSKYNRLLEIENIL-------GYSAEYAG
PELRGVMGRR-----
>Treponema [Treponema pallidum] (Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Treponema; pallidum)
-----------------------------------------------------XSDIACI
EAREIIDSRGNPTVEVDVSLS-DG---SFGRACVPSGASTGEFEALEMRDGDKERYNGKG
VLKAVGTVNTLIADTLEG--MDALNQGEIDHAMR-NLDGTDN-----K--SKLGANAMLG
VSMACARAAADFLGVPLYRYL-----GGVH-----------TFRMPVPMANIINGGKHSD
-NKIDFQEFMVMPIGAASMREAVRMTAEVFHALKGLLAAD-GKAT-SVGDEGGFAPDL-D
NEQALEYIMKAIAKAGLAPR--------KD--VCIALDCASSELFDEGDRRGYKFWKSN-
-----PGKLFTAQEMIDLYKKW---IATYP-IVSIEDPLDQNDWAGYVQLTKEL---GDK
VQIVGDDFFVTNTGRLARGIKEGSCNSILIKLNQIGTVTETVDAVRMAQNAGYAAVISHR
SGETEDAFIADLAVALETGQIKTGSMSRSDRVAKYNQLMRIEEEL-------GAQARYYG
AKTFERFGC------
>Euglena [Euglena gracilis] (Eukaryota; Euglenozoa; Euglenida; Euglenales; Euglena; gracilis)
FFSILPIMANNTADIQYLRQHNIPELVNDLIQQLVTTKPAQPVAFLRDVLSKRKAVIKVV
KARQILDSRGNPTVEVDVILD-NG---VVGRGAVPSGASTGEYEAVELRDGDKKVYLGKG
VLKSVNAVNTLVAPKLIG--LDPANQREIDELMK-QIDGTPN-----K--GKIGANGILG
VSMACCRAAALTQGIPLWKHI-----ANLHGNKD-------NFQLPVPMCNIINGGKHAD
-NKIDFQEFMIMPIGAKSFSEGLRWVTEIFHTLKALLKKA-GHVT-SVGDEGGFAPDL-S
NDEALEFVMKAIKAAGYTPG--------TQ--IGVALDCASSELFDEGGRKGYKFWKSN-
-----PSKLFSAQEMIDIFCRW---CDEYP-IVSIEDPLDQNDWDGYVNMTKKM---GRR
TQIVGDDFFVTNPARFSKGIGMNACNAILIKVNQIGTVSETLECIKMAQAHGYGSIASHR
SGETEDAFIADLAVGTGCGQIKTGSLSRTDRMAKYNQLIRIEEEL-------GAQAKWTT
KHLVR----------
>Anabaena [Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120)] (Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc; sp.)
------------------------------------------------XNNIVDTAIEAI
VAREILDSRGRPTIEAEVHLL-SG---AVGLAQVPSGASTGTFEAHELRDKDKSRYGGKG
VLKAVHNVNEILAPKLID--LDALNQELIDRTMI-ALDGSGN-----K--SNLGANAILA
VSLAAARAGAESLGIPLYRYL-----GGPL-----------ANLLPVPLMNVINGGAHAS
-NNVDFQEFMIVPVGATSFREALRWGAEVFATLSEVLHDK-GLLT-GVGDEGGFAPNLES
NQVALELLVAAIEKAGYKPG--------EQ--VALALDVAASEFY---KEGQYVY-----
-----DGRPHAPTEFIDYLGQL---VDQYP-IVSIEDGLHEEDWQHWQLLTQKV---GSR
VQLVGDDLFVTNATRLQKGIQEKAGNAILIKLNQIGSLTETLETIDLGTRNGFRSVISHR
SGETEDTTIADLAVATRAGQIKTGSLCRSERVAKYNRLLRIEDEL-------GDRAVYAG
AVGLGPK--------
>Synechocystis [Synechocystis sp. PCC 6803] (Bacteria; Cyanobacteria; Chroococcales; Synechocystis; sp.)
------------------------------------------------XLSKVPATIEEI
AAREILDSRGRPTIEAEVRLE-SG---AHGIAQVPSGASTGSFEAHELRDGDPKRYDGKG
VEKAVRNVTEKIAPVVEG--LDAFDQMAVDQAMI-DRDGTDN-----K--KELGANAILG
VSLATAKAAAAELAIPLYRYL-----GGPL-----------ANVLPVPMMNVINGGAHAD
-NNVDFQEFMIMPVGAETFKEALRWGAEVFAVLGKVLKER-KLLSGGVGDEGGYAPNLTS
NQQALDILIEAIEQAGYKPG--------SQ--IALAMDIAASEFF---KNGQYEY-----
-----DGGSHSPQEFIDYQAKL---VSQYP-IVSIEDGLHEDDWESWKGLTTSL---GTK
TQLVGDDLMVTNPVRLQKSIDLGVANAILIKLNQIGTLSETLETISLATRHSYRSVISHR
SGETEDTTIADLAVATRVGQIKTGSLCRSERVAKYNRLLRIEDEL-------GDRAVYAP
KIGLGPKHS------
>Dehalococcoides [Dehalococcoides ethenogenes 195] (Bacteria; Chloroflexi; Dehalococcoidetes; Dehalococcoides; ethenogenes)
----------------------------------------------------XSAVVKSI
KAREILDSRGNPTVEADVVLS-DG---SFGRAAVPSGASTGSHEAVELRDGDKSRYNGLG
VQKAVTNVNTAIAKAISG--FKASDQQGLDNLLI-ELDGTPN-----K--AKLGANAMLA
TSLAVAHAAAASCHMPLYRYL-----NNCD-----------EYILPVPMFNILNGGKHAS
-NSTDFQEFMVMPTGAKSFAEALRMGTEVYHSLKKVLKGM-NQNT-TVGDEGGFAPSLPT
NKDAVEVILKAIEKAGYRPG--------ED--IFIALDPASSELY---QDGKYTLAT---
-----ENKTLSSAEMVDYWCGW---VEKYP-IISIEDGLFEDDWDGWKMLTKKI---GSK
VQLVGDDFYVTNIKRLERGIKENASNSILIKLNQIGTLSETIAAIKMANNSAWTAVVSHR
SGETEDTTIADLAVAMNAGQIKTGAPCRAERTAKYNRLLRIEEEL-------GGKAKYPG
KEAFFNLK-------
>Xylella [Xylella fastidiosa 9a5c] (Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales; Xanthomonadaceae; Xylella; fastidiosa)
----------------------XGPELFCESRYRDDNPMVLWYCSLLWLLTGPMTAIAKI
YAREILDSRGNPTLEAEVTLE-NA---VCGRAAVPSGASTGTKEAVELRDGDKTRYLGKG
VRAAVDNVNGVIAAALVG--FDGADQTGLDHRLI-NLDGTEN-----K--GRLGANALLG
VSLATAHAVAAARKQPLWMYL-----STLGES---------KVSLPVPMMNIINGGAHAD
-NNVDFQEFMVLPVGFASFSEALRAGTEIFHALKSVLKGQ-GLST-AVGDEGGFAPDLRS
NVEALDAILEAIGRAGYIAG--------ED--VLLGLDVASSEFR---DNGKYNLVG---
-----ENKRLTSEQFVDFLDDW---VTQYP-IISIEDGLAEDDWAGWKQLTERI---GHK
VQLVGDDLFVTNPKVFQEGITSGIANAILIKLNQIGTLTETLESIAMAHRAQYAAIVSHR
SGETEDTSIADIAVATTATQIKTGSLCRSDRVAKYNQLLRIEQAL-------GVGARYAG
RDAFVSLKS------
>Porphyromonas [Porphyromonas gingivalis W83] (Bacteria; Bacteroidetes; Bacteroidetes (class); Bacteroidales; Porphyromonadaceae; Porphyromonas; gingivalis)
------------------------------------------------------XEIAKI
IGREILDSRGNPTVEVDVHLA-CG---IIGRAAVPSGASTGENEAIELRDQDKARYCGKG
VLKAVKNVNEVIDPALCG--MSVLEQTAIDRKLI-ELDGTKT-----K--SNLGANAMLG
VSLAVAKAAAAYLDIPLYRYI-----GGSN-----------TYVLPVPMMNIINGGSHSD
-APIAFQEFMIRPVGACCFREGLRMGAEVFHALKKVLHDR-GLST-AVGDEGGFAPALNG
TEDAIESILKAVEAAGYVPG--------KD--ITIAMDCASSEFF---KDGIYDYTKFEG
E----KGKKRSIDEQVAYLTEL---VGKYP-IDSIEDGMSENDWEGWKKLTVAL---GDK
VQLVGDDLFVTNVEFLRRGIAEKCGNSILIKVNQIGTLTETLNAIEMAHRHGFTSVTSHR
SGETEDTTIADIAVATNSGQIKTGSLSRTDRMAKYNQLLRIEEEL-------GPCAVYGY
KKV------------
>Streptococcus [Streptococcus pyogenes MGAS5005] (Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus; pyogenes)
-----------------------------------------------------XSIITDV
YAREVLDSRGNPTLEVEVYTE-SG---AFGRGMVPSGASTGEHEAVELRDVSKARYLGLG
TQKAVDNVNNIIAEAIIG--YDVRDQQAIDRAMI-ALDGTPN-----K--GKLGANAILG
VSIAVARAAADYLEVPLYTYL-----GGFN-----------TKVLPTPMMNIINGGSHSD
-APIAFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKER-GLVT-AVGDEGGFAPKFEG
TEDGVETILKAIEAAGYEA---------GENGIMIGFDCASSEFY-DKERKVYDYTKFEG
E----GAAVRTSAEQVDYLEEL---VNKYP-IITIEDGMDENDWDGWKVLTERL---GKR
VQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHR
SGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQL-------GEVAQYKG
IKSFYNLKK------
>Chlorobium [Chlorobium tepidum TLS] (Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; Chlorobaculum; Chlorobium; tepidum)
-----------------------------------------------------XSVITRI
HARQIMDSRGNPTVEVDVHTE-SS----FGRAAVPSGASTGVHEAVELRDKDKSVFLGKG
VLKAVENVNTLINDALLG--MDVTEQEAIDAKLI-ELDGTPN-----K--SKLGANAILG
VSLACAKAGAEYSALPLYRYI-----GGTT-----------AKTLPVPMMNVLNGGAHAD
-NTVDFQEFMIMPIGFERYSDALRCGAEVFHSLKSLLHDR-GLST-AVGDEGGFAPNVES
NEQAIELVIEAIGMAGYKAGAPTDRGGLGDGHVMIALDPASSEFY-DAEKKKYVFKKS--
-----SGRELSSEEMASYWADW---ASRYP-IISIEDGMAEDDWEGWKMLTDKI---GGR
VQLVGDDLFVTNSKRLAEGIEKGVGNSILIKVNQIGTLTETLQAIELAKRNGYTSVISHR
SGETEDTTIAQIAVATNAGQIKTGSMSRSDRMAKYNELLRIEEEL-------GSTALYPG
IGAFRV---------
>Thiobacillus [Thiobacillus denitrificans ATCC 25259] (Bacteria; Proteobacteria; Betaproteobacteria; Hydrogenophilales; Hydrogenophilaceae; Thiobacillus; denitrificans)
-----------------------------------------------------XSAIIDV
IAREILDSRGNPTVEADVLLE-SG---VIGRAAVPSGASTGSREAIELRDGDKSRYLGKG
VLKAVEHVNTEICEAIIG--LDVEDQAFIDQTMI-ELDGTEN-----K--SRLGANALLA
VSMACARAAAEQAGLPLYRYL-----GGAA-----------PMQLPVPMMNIINGGAHAN
-NNIDMQEFMVIPVGAPSFREALRYGAEVFHALKKLLDDA-GMTT-TVGDEGGFAPNLES
HEAALKLIVQAIEKAGLQPG--------ID--VAIGVDCASSEFY---KDGLYHIDS---
-----ENLKLTSAAFTDYLAAW---CDKYP-IISIEDGMAEGDWDGWKILTDRL---GRR
VQLVGDDLFVTNAKILKEGIEKDIANSILIKVNQIGTLSETFQAIEMAKQAGYTSVISHR
SGETEDTTIADLAVATNARQIKTGSLSRSDRMAKYNQLLRIEEEL-------GDTASYPG
RDAFRQRG-------
>Campylobacter [Campylobacter jejuni RM1221] (Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Campylobacteraceae; Campylobacter; jejuni)
-----------------------------------------------------XLVIEDV
RAYEVLDSRGNPTVKAEVTLS-DG---SVGAAIVPSGASTGSKEALELRDND-ERFGGKG
VLKAVANVNETIADEILG--LDAFNQTQLDDTLR-ELDGTNN-----Y--SNLGANATLG
VSMATARAAAAALGMPLYRYL-----GGAN-----------ASILPVPMCNIINGGAHAN
-NNVDFQEFMIMPFGFTSFKEALRSVCEIYVILKKELANS-GHST-ALGDEGGFAPNLAN
NTEPIDLLMTCIKKAGYE----------NR--VKIALDVASTEFF---KDGKYHM-----
-----EGKAFSSEDLIERYVEL---CAKYP-ICSIEDGLAENDFEGWIKLTEKL---GNK
IQLVGDDLFVTNEDILREGIIKKMANAVLIKPNQIGTITQTMRTVRLAQRNNYKCVMSHR
SGESEDAFIADFAVALNTGQIKTGALARGERTAKYNRLLEIELES----------DEYLG
EKL------------
>Methanosarcina [Methanosarcina mazei Go1] (Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; mazei)
------------------------------------------XSYIGLQQDSGEYKIQKI
HAREILDSRGNPTVEVDVFTP-KG---F-GRASVPSGASTGTNEALELRDADPNRYGGKG
VLTAVKNVNTIIQKELLG--LDVRNQREIDELMI-ELDETEN-----K--SNLGANAILG
VSMAVAKAAADSLNIPLYRYF-----GGSN-----------AFTLPVPTMNVLNGGKHAG
-NELAIQEFMIQPKGAETFYEALQIGAEIYQTLGKFLENKYGRSSTNVGYEGGYAPKMGE
STEALDALVHAIEEAGYTE---------SE--VTIGLDAAATEFY---EEEFYNI-----
-----DGKKLAAPELLDYYVEL---VNSYP-ILSIEDPFYEEAFEDFEALTNEL----WD
TIIVGDDLFVTNIERLSKGVDMGAANALLLKVNQIGSISEAFDAASMASRNGYTVIVSHR
SAETEDTTISDLAVAIGAEMIKTGAPARGERTAKYNQLLRIEEDL-------GEVAHYVQ
L--------------
>Methanocaldococcus gi|1590967|gb|AAB98220.1| Methanocaldococcus jannaschii DSM 2661, complete genome
----------------------------------------------MLYNMDERFEIKDI
VAREVIDSRGNPTVEVEVITKGNG---Y-GSAIVPSGASTGTHEALELRDKE-KRFGGKG
VLMAVENVNSIIRPEILG--YDARMQREIDTIMI-ELDGTPN-----K--SRLGANAILA
VSLAVAKAAAATAKIPLYKYL-----GGFN-----------SYVMPVPMMNVINGGKHAG
-NDLDLQEFMIMPVGATSISEAVRMGSEVYHVLKNVILEKYGKNAVNVGDEGGFAPPLKT
SREALDLLTESVKKAGYE----------DE--VVFALDAAASEFY---KDGYYYV-----
-----EGKKLTREELLDYYKAL---VDEYP-IVSIEDPFHEEDFEGFAMITKEL-----D
IQIVGDDLFVTNVERLRKGIEMKAANALLLKVNQIGTLSEAVDAAQLAFRNGYGVVVSHR
SGETEDTTIADLSVALNSGQIKTGAPARGERTAKYNQLIRIEQEL--------GLSKYAG
RNFRCPF--------
>Pyrococcus [Pyrococcus furiosus DSM 3638] (Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus; furiosus)
--------------------------------------------------XENPYEIVGV
VAREILDSRGNPTVEVDVYTH-VG---M-GRAAVPSGASTGTHEALELRDGG-KRYHGKG
VRRAVENVNKIIAPELIG--MDVRWQREIDALLL-ELDGTEN-----K--SNVGANAILA
VSLAVAKAAANSLELPLYQYL-----GGVN-----------AYVLPVPLSNVINGGVHAG
-NDLDFQEFMIMPIGADSFREAIRWVSETYHVLKKVIMEKYGKNAVNVGDEGGFAPPMKE
VTEPLDVLIKAIEEAGYKPG--------DE--IALALDVASSELF-NEETGKYVV-----
-----GGKEYDRGELLELYKDL---TSTYP-IVSIEDPFHEEDWEGFVMITKEL---GHK
VQIVGDDLFVTNPKRLRKGIELGAANALLLKVNQIGTLSEAMDAAFTAFRAGYGVIVSHR
SGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL-------EGVAVYAG
KRFRKVFF-------
>Arabidopsis1 [Arabidopsis thaliana (thale cress)] (Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis; thaliana)
----------XSVQEYLDKHMLSRKIEDAVNAAVRAKTSDPVLFIANHLKKAVSSVITKV
KARQILDSRGIPTVEVDLHTN-KG---V-FRASVPSGDSSGTYEAIELRDGDKGMYLGNS
VAKAVKNINEKISEALIG--MDPKLQGQIDQAMI-DLDKTEK-----K--SELGANAILA
VSIAACKAGAAEKEVPLCKHL-----SDLSGRA--------NMVLPVPAFTVLSGGKHAS
-NTFAIQEIMILPIGASRFEEALQWGSETYHHLKAVISEKNGGLGCNVGEDGGLAPDISS
LKEGLELVKEAINRTGYN----------DK--IKIAIDIAATNFC---LGTKYDLDIKSP
NKS--GQNFKSAEDMIDMYKEI---CNDYP-IVSIEDPFDKEDWE-HTKYFSSL---GI-
CQVVGDDLLMSNSKRVERAIQESSCNALLLKVNQIGTVTEAIEVVKMARDAQWGVVTSHR
CGETEDSFISDLSVGLATGVIKAGAPCRGERTMKYNQLLRIEEEL-------GDQAVYAG
EDWKLSL--------
>Dictyostelium [Dictyostelium discoideum AX4] (Eukaryota; Mycetozoa; Dictyosteliida; Dictyostelium; discoideum)
------------------------------------------------------XSIESI
KAREILDSRGNPTLEVEVWTS-EG---M-FSAKVPSGASTGIHEAFELRDGDKSRYFGYG
VLNAIVNVNNLISPTLKG--MRVDNQKAIDDKMI-ELDGTKN-----K--SKLGSNAIVG
VSMAVARAAASIKGVPLYRYI-----SQLAGNS--------NIRLPVPCFNVINGGKHAG
-NRLPFQEFMLVPIGAPKFKEALRYGSEVYHSLKEIIKERYGLDATNVGDEGGFAPNLTS
PEEALTLLVDAINHSGYQ----------DV--IKIGIDSAASEFW-NPKTSKYDMDFKNI
GSSHLKSSLNSGEQLMSRYLEI---LKKYP-IAFFEDPFGEDDWENHGKITAAI---GNK
IQIIGDDLLCTNPERIKKAISEKTVNSLLLKINQIGTLTETIEAAKLAKEAGWGCLVSHR
SGETDDHFIADLVVGLGTGEIKSGAPCRFERLSKYNRLMKIEEELEKLHRSNGNSFEYAG
EEFYHF---------
>Leishmania [Leishmania major] (Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Leishmania; major)
------------------------------------------------------XPIRKV
YAREVLDSRGNPTVEVELMTE-AG---V-FRSAVPSGASTGVHEACELRDGDKARYCGAG
CTQAVKNVNEILAPALVG--KEESDQAGLDKMMC-ELDGTKN-----K--SKLGANAILG
CSMAISKAAAAKAGVPLYRYI-----ASLAGTK--------DIRLPVPCFNVINGGKHAG
-NILPFQEFMIAPTKATSFREALRMGSEVYHALKVIIKSKYGQDAVNVGDEGGFAPPIKH
IDEPLPILMEAIEKAGHK----------GK--FAICMDCAASEAY-DAERKMYNLTFKNP
-----EPTYVSAAELQATYERW---VAEYP-LVSIEDPFAEDNFDEFSAITKAL---AGK
AQIVGDDLTVTNVKRVTMAIEKSACNSLLLKINQIGTISESIAAAKLCMENGWSVMVSHR
SGETEDTYIADLSVGLGTGQIKTGAPCRGERTAKLNQLLRIEEEI-------GSTATYGY
PGWA-----------
>Entamoeba [Entamoeba histolytica] (Eukaryota; Entamoebidae; Entamoeba; histolytica)
------------------------------------------------------XSIQKV
HAREILDSRGNPTIEVEITTG-KG---M-FRSCVPSGASTGVHEAVELRDGDKKRYGGKG
VLKAVENVNTIIGPALLG--KNVLNQAELDEMMI-KLDGTNN-----K--GKLGANAILG
CSMSICRAAAAEKGLPLYKYL-----AELTGHK--------EMTMPVPCFNVINGGAHAG
-NALAMQEFMICPTGATNFHEALRMAAETYQCLKVVIKAKYGQDATNVGDEGGFAPNVSG
AREALDLLVEAIAKAGYT----------GK--IEIAMDCAASEFY-NEETKKYDLGKKIP
ADKKDPSLVKDVDGLIAEYVDY---GKHYP-IASIEDPFAEDDWAAWNKFTVEH---GN-
FQIVGDDLLVTNPARVQMAMDKNACNSVLIKVNQIGTLTETFKTIKMAQEKGWGVMASHR
SGETEDTFIADLVVGLNCKQIKTGAPCRSERLCKYNQLMRIEEEL-------GN-IPYAG
KNWRNSTA-------
>Mastigamoeba [Mastigamoeba balamuthi] (Eukaryota; Pelobiontida; Mastigamoebidae; Mastigamoeba; balamuthi)
-----------------------------------------------------XSTIKSV
FAREILDSRGNPTVEVDLTTE-KG---L-FRSAVPSGASTGIYEACELRDGDKSRYLGKG
VLKAVENVNKILAPKLIG--LDVTKQGEIDRLML-QIDGTEN-----K--THLGANAILG
CSMSVCRAAAAFRGLPLYRYI-----AELSGNK--------SPMLPLPCFNVINGGEHAG
-NKLAMQEFMICPTGATSFHEALRMAAETYHNLKLVIKKRYGMDATNVGDEGGFAPNIQA
NHEGLELIVEAIKQAGYT----------GK--IEIGMDVAASSFW-DAKESKYDLGFKVP
ADKKTPDMLVSGEGLIKLYEEW---TSKYP-IWSIEDPFDQDDWATYTRFTELI---RNR
IQIVGDDLLVTNPKRIVEARNKKACNALLLKLNQIGSVSEAVEACRLAREVNWGVMVSHR
SGETEDAFIADLVVGLGCGQIKTGAPCRSERLAKYNQLLRIEEEL-------GANAHYAA
KTLSGVGH-------
>Plasmodium [Plasmodium falciparum (malaria parasite P. falciparum)] (Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodium; Plasmodium (Laverania); Plasmodium; falciparum)
----------------------------------------------------XAHVITRI
NAREILDSRGNPTVEVDLETN-LG---I-FRAAVPSGASTGIYEALELRDNDKSRYLGKG
VQKAIKNINEIIAPKLIG--MNCTEQKKIDNLMVEELDGSKNEWGWSK--SKLGANAILA
ISMAVCRAGAAANKVSLYKYL-----AQLAGKKSD------QMVLPVPCLNVINGGSHAG
-NKLSFQEFMIVPVGAPSFKEALRYGAEVYHTLKSEIKKKYGIDATNVGDEGGFAPNILN
ANEALDLLVTAIKSAGYE----------GK--VKIAMDVAASEFY-NSENKTYDLDFKTP
NND--KSLVKTGAQLVDLYIDL---VKKYP-IVSIEDPFDQDDWENYAKLTAAI---GKD
VQIVGDDLLVTNPTRITKALEKNACNALPLKVNQIGSITEAIEACLLSQKNNWGVMVSHR
SGETEDVFIADLVVALRTGQIKTGAPCRSERNAKYNQLLRIEESL-------GNNAVFAG
EKFRLQLN-------
>Arabidopsis2 [Arabidopsis thaliana (thale cress)] (Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis; thaliana)
------XALTTKPHHLQRSFLSPSRVSGERYLESAPSCLRFRRSGVQCSVVAKECRVKGV
KARQIIDSRGNPTVEVDLITD-D----L-YRSAVPSGASTGIYEALELRDGDKSVYGGKG
VLQAIKNINELVAPKLIG--VDVRNQADVDALML-ELDGTPN-----K--SKLGANAILG
VSLSVCRAGAGAKGVPLYKHI-----QETSGTK--------ELVMPVPAFNVINGGSHAG
-NSLAMQEFMILPVGATSFSEAFQMGSEVYHTLKGIIKTKYGQDACNVGDEGGFAPNVQD
NREGLVLLIDAIEKAGYT----------GK--IKIGMDVAASEFF--MKDGRYDLNFKKQ
PND--GAHVLSAESLADLYREF---IKDFP-IVSIEDPFDQDDWSSWASLQSSV-----D
IQLVGDDLLVTNPKRIAEAIKKQSCNALLLKVNQIGTVTESIQAALDSKAAGWGVMVSHR
SGETEDNFIADLSVGLASGQIKTGAPCRSERLSKYNQLLRIEEEL-------GN-VRYAG
EAFRSP---------
>Cladosporidium [Davidiella tassiana (anamorph: Cladosporium herbarum)] (Eukaryota; Fungi; Ascomycota; Pezizomycotina; Dothideomycetes et; Chaetothyriomycetes incertae sedis; Mycosphaerellaceae; Davidiella; tassiana)
------------------------------------------------------XPISKI
HSRYVYDSRGNPTVEVDIVTE-TG---L-HRAIVPSVASTGSHEACELRDGDKSKWAGKG
VTKAVANVNEIIAPALIKENLDVKDQAAVDAFLN-KLDGTTN-----K--TKIGANAILG
VSMAVAKAAAAEKRVPLYAHI-----SDLSGTKK-------PFVLPVPFMNVVNGGSHAG
-GRLAFQEFMIVPSGAPSFTEAMRQGAEVYQKLKSLTKKRYGQSAGNVGDEGGVAPDIQT
AEEALDLITDAIEEAGYT----------GQ--IKIAMDVASSEFY-KADEKKYDLDFKNP
DSD--KSKWITYEQLADQYNEL---AAKYP-IVSIEDPFAEDDWEAWSYFYKTS---GSD
FQIVGDDLTVTNPEFIKKAIETKACNALLLKVNQIGTITEAINAAKDSFAAGWGVMVSHR
SGETEDVTIADIVVGLRAGQIKTGAPARSERLAKLNQILRIEEEL-------GDKRLYAG
DNFRTAINL------
>Saccharomyces [Saccharomyces cerevisiae (baker's yeast)] (Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; cerevisiae)
------------------------------------------------------XAVSKV
YARSVYDSRGNPTVEVELTTE-KG---V-FRSIVPSGASTGVHEALEMRDEDKSKWMGKG
VMNAVNNVNNVIAAAFVKANLDVKDQKAVDDFLL-SLDGTAN-----K--SKLGANAILG
VSMAAARAAAAEKNVPLYQHL-----ADLSKSKTS------PYVLPVPFLNVLNGGSHAG
-GALALQEFMIAPTGAKTFAEAMRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQT
AEEALDLIVDAIKAAGHD----------GK--VKIGLDCASSEFF---KDGKYDLDFKNP
ESD--KSKWLTGVELADMYHSL---MKRYP-IVSIEDPFAEDDWEAWSHFFKTA---G--
IQIVADDLTVTNPARIATAIEKKAADALLLKVNQIGTLSESIKAAQDSFAANWGVMVSHR
SGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEEL-------GDKAVYAG
ENFHHGDKL------
>Candida [Candida albicans] (Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; mitosporic Saccharomycetales; Candida; albicans)
-----------------------------------------------------XSYATKI
HARYVYDSRGNPTVEVDFTTD-KG---L-FRSIVPSGASTGVHEALELRDGDKSKWLGKG
VLKAVANVNDIIAPALIKAKIDVVDQAKIDEFLL-SLDGTPN-----K--SKLGANAILG
VSLAAANAAAAAQGIPLYKHI-----ANISNAKKG------KFVLPVPFQNVLNGGSHAG
-GALAFQEFMIAPTGVSTFSEALRIGSEVYHNLKSLTKKKYGQSAGNVGDEGGVAPDIKT
PKEALDLIMDAIDKAGYK----------GK--VGIAMDVASSEFY---KDGKYDLDFKNP
ESD--PSKWLSGPQLADLYEQL---ISEYP-IVSIEDPFAEDDWDAWVHFFERV---GDK
IQIVGDDLTVTNPTRIKTAIEKKAANALLLKVNQIGTLTESIQAANDSYAAGWGVMVSHR
SGETEDTFIADLSVGLRSGQIKTGAPARSERLAKLNQILRIEEEL-------GSEAIYAG
KDFQKASQL------
>Phytophthora [Phytophthora infestans (potato late blight agent)] (Eukaryota; stramenopiles; Oomycetes; Peronosporales; Phytophthora; infestans)
-----------------------------------------------------XVSIVSI
KARQIFDSRGNPTVEVDLVTE-LG----EYRAAVPSGASTGEFEALEMRDGG-KDYMGKG
VLNAVKNVNEIIAPALIG--KDVTKQAEIDRFMVEKLDGTQNEWGWYK--KKLGANAILG
VSLALCRAGAAAKKQPLWQHI-----ADLAGNP--------TPCLPVPSFNIINGGSHAG
-NKLAMQEFMILPVGAKNFTEAMKIGSEVYHNLKKVIKGRYGLDATAVGDEGGFAPNIQS
NGEAIDLIEEAIKAAGYT----------NQ--VRLGMDVAASEFYTGAEDARYNLDFKNE
NAA--ESEKIPADKLLEVYEGFIAKCADSSKIVSIEDPFDQDDWESWVKITGKV---GKD
VQIVGDDLTVTNPTRVKKAIEQKACNALLLKVNQIGSITESIEAVTMAKKAGWGIMASHR
SGETEDTFIADLAVGLSAGQIKTGAPCRSERLAKYNQLLRIEEEL-------GNKARYAG
EDFRDVEKLGKYSTF
>Cunninghamella [Cunninghamella elegans] (Eukaryota; Fungi; Zygomycota; Zygomycetes; Mucorales; Cunninghamellaceae; Cunninghamella; elegans)
------------------------------------------------------STITKV
HARQIFDSRGNPTVEVEVTTD-KG---V-FRAGVPSGASTGVHEALELRDGVKSDYLGKG
VLKAVGNVNTIINEELVKANLSVVDQKAVDDFLI-QLDGTEN-----K--EKLGANAILG
VSLAVAKAGAAEKGVPFYVHI-----ADLAGSKK-------PFVLPVPAFNVINGGSHAG
-NKLAMQEFMIMPTGAKSFSEAMKLGSEVYHTLKKVINEKYGQDATNVGDEGGFAPNIQD
NQEGLELLVTAIEKAGYT----------GK--IKVAMDCAASDFY---KDGKYDLDFKNP
NSD--PSTYLTGQDLTDLYNSY---AGKYP-IVSIEDAFDQDDWENWAHMNASA-----D
YQLVGDDLTVTNPKRIATAVEKKACNALLLKVNQIGTLTESIQAALDSQKAGWGVMVSHR
SGETEDTSIASIVVGLRTGQIKTGAPCRSERLAKYNELLRIEEEL-------GDAAIYAG
EHFRKAHDL------
>Neocallimastix [Neocallimastix frontalis] (Eukaryota; Fungi; Chytridiomycota; Neocallimastigales; Neocallimastigaceae; Neocallimastix; frontalis)
------------------------------------------------------XAITKV
HARQIFDSRGNPTVEVEVTTD-KG---L-FRAAVPSGASTGVHEALELRDGIKADYVGKG
VLKAVENVNKTIAPALVAANLDVKNQKAVDDFLL-KLDGTPN-----K--SKLGANAILG
VSLAVARAGAADKGVPLYQHL-----GELAGNKG-------PWILPVPSMNVLNGGSHAG
-NKLAMQEFMILPTGAKSFTEALKMGSEVYHALKSVIKAKYGQDACNVGDEGGFAPNIQD
NKEGLELLNEAIAKAGYT----------GK--VKIGMDVASSEFY---KDGKYDLDFKNP
NSD--PSKWISGEELGQFYKEI---TSEYP-IVSIEDPYDQDDFESWSKFRADM---QDK
IQIVGDDLTVTNPKRIAMAIEKKACNGLLLKVNQIGTVSESIQAALDAFNDGWGVMVSHR
SGETEDTFIADLVVGLKSGQIKTGAPCRSERLAKYNQLLRIEEEL-------GANATYAG
ENFRRPF--------
>Arabidopsis3 [Arabidopsis thaliana (thale cress)] (Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis; thaliana)
-----------------------------------------------------XATITVV
KARQIFDSRGNPTVEVDIHTS-NG---IKVTAAVPSGASTGIYEALELRDGG-SDYLGKG
VSKAVGNVNNVIGPALIG--KDPTQQTAIDNFMVHELDGTQNEWGWCK--QKLGANAILA
VSLAVCKAGAVVSGIPLYKHI-----ANLAGNP--------KIVLPVPAFNVINGGSHAG
-NKLAMQEFMILPVGAASFKEAMKMGVEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQE
NKEGLELLKTAIEKAGYT----------GK--VVIGMDVAASEFY--SEDKTYDLNFKEE
NNN--GSQKISGDALKDLYKSF---VAEYP-IVSIEDPFDQDDWEHYAKMTTEC---GTE
VQIVGDDLLVTNPKRVAKAIAEKSCNALLLKVNQIGSVTESIEAVKMSKKAGWGVMTSHR
SGETKDTFIADLAVGLSTGQIKTGAPCRSERLAKYNQLLRIEEEL-------GSEAIYAG
VNFRKPVEPY-----
>Alligator [Alligator mississippiensis (American alligator)] (Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archosauria; Crocodylidae; Alligatorinae; Alligator; mississippiensis)
------------------------------------------------------------
----------------DLYTS-KG---L-FRAAVPSGASTGIYEALELRDNDKTRFMGKG
VSKAVAHVNKTIAPALISKNISVVEQEKIDRLML-EMDGSEN-----K--SKFGANAILG
VSLAVCKAGAAEKGVPLYRHI-----ADLAGNP--------EVILPVPAFNVINGGSHAG
-NKLAMQEFMILPVGAESFKEAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILE
NKEALELLKNAINKAGYS----------DK--IVIGMDVAASEFY---RDGKYDLDFKSP
DD---PSRYITPDQLADLYKSF---VKNYP-VVSIEDPFDQDDWAAWKKFTASV---G--
IQVVGDDLTVTNPKRIAKAVDDKACNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHR
SGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEEL---------------
---------------
>Thermoplasma [Thermoplasma acidophilum] (Archaea; Euryarchaeota; Thermoplasmata; Thermoplasmatales; Thermoplasmataceae; Thermoplasma; acidophilum)
----------------------------------------------------XELPIEEI
KVRKVLDSRGNFTVEADVTVP-NG----FGRTSAPAGASTGETEVIAFSKS--------G
IDASIQFFESKVKRSLIG--FNALDQSGFDKLLT-DIDGSGN-----F--SNLGGNLATA
LSMSVAKAAAQSLGIPLYRYV-----GGI------------RSTIPRPMGNVIGGGKHAR
-NGTSIQEFLVSAQGS-TFLESAYINVLVHRRIGDMLSDKFKDISIGVGDERTWSVNL-S
DEEAFEILNEAVKEISSEKK--------VK--IYTGVDFAADSLY---ENGKYVY-----
-----KHTTKSRDEQIDYAISI---SKDFG-VYYIEDPMYDTDFDGFAEITARI---GDR
SLIVGDDLYTTNPDRIRKGVEKKSTNAVLIKVNQIGTLSAAREAVAVATFAGMKNIVSHR
SGETTDDFLAHLSVAFGSTFVKTGVIG-GERVAKLNEIARIEECL-------TS------
---------------
>Archaeoglobus [Archaeoglobus fulgidus DSM 4304] (Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae; Archaeoglobus; fulgidus)
------------------------------------------------------------
--------------------------------XAPSGASTGSGEAVVV---SPYRY----
-----EEIEEEVSKAIIG--MSVFDQESVDEALR-ELDGTDN-----F--SRIGGNFAIT
ASLAVAKAAAEILGLPLYAYV-----GGVF-----------AKELPYPLGNVIGGGRHAE
-GSTSIQEFLVIPVGAKTFFEAQRANAAVHKQLKKIFKER-GIFAAK-GDEGAWAAQI-S
DEQAFEILSEAIQRVEDELG--------VK--VRMGIDVAATELW---DGERYVY-----
-----SDRKLTTEEQIAYMAEL---ADRYD-LLYIEDPLHEKDFEGFAELTKQV-----K
CMVCGDDIFVTNPEIIKKGIEVGAANTVLIKPNQNGTLSGTAKAVKIAKDNGYSVVVSHR
SGETEDETLAHLAVAFNAKLIKTGVVG-GERISKLNELIRIEELM--------DKPRMVM
I--------------
>Methanothermobacter [Methanothermobacter thermautotrophicus str. Delta H] ((Methanobacterium thermoautotrophicum str; deltaH); Archaea; Euryarchaeota; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanothermobacter; thermautotrophicus)
----------------------------------------------------XESIIEDV
RVRKILDSRGNPTVEVDVITW-NG----FGRAAAPSGASTGSREVAAFPSG--------G
VDEIITEVEDIISSELIG--MDAVDLQDIDLVLK-EIDGTEN-----L--SSLGGNTVVA
VSMATAKAAASSYNMPLYRFL-----GGNL-----------ATSIPYPLGNMINGGAHAG
KNAPDIQEFLVVPVGAEDITEAVFANAAVHKRIRELIQKKDPSFAGGKGDEGGWVPSL-S
NGDALEIQATACEEVTDELG--------VE--VRPSLDLAASEFW-DPEIEKYVYRQ---
-----ENVQKDTGEQIEFVKEI---IETYD-MYYVEDPLHEGDLEGFAELTSLV---GDR
CMICGDDIFVTNREILREGIEMGAANAIIIKPNQIGTLTDTYLTVKLALENRYTPVVSHR
SGETTDDTIAHLAVAFGAPLIKTGAIG-GERIAKLNELIRIQEEI-----------PYSR
MADLPF---------
>Haloarcula [Haloarcula marismortui] (Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Haloarcula; marismortui)
-----------------------------------------------------XTLITDI
RLRRVLDSRGNATVEADVLTE-SG---GFGRGKAPSGASTGEYEAIELPANE--------
---AIAKAREEALPRLIGE-VHAGNQRDVDTALH-AADGTDD-----F--SGIGANSAVA
ISMAAAKAGADVLGAPLYQHL-----GGTFR----------GNEYPTPLGNII-GGEHAA
-DATNIQEFLAAPVGAPSVEEAVFANAAVHQEVHDILADR-DLPAGK-GDEGAWAPSV-S
DDEAFEIMDEAVETVADDFG--------FA--ISFGLDVARAELY-DDEADGYVY-----
-----DDGVKSTEEQIEYIAGK---VEEYD-LVYVEDPLDENDYEAFADLTAQV---GDQ
TLVCGDDLFVTNVERLQAGINADAGNSILIKPNQIGTLTDAVDAIELATASGYESVVSHR
SGETEDTTIAHLAVATDAPFIKTGAVG-GERTAKLNELIRIEDNA-----------V---
---------------
>Halobacterium [Halobacterium sp. NRC-1] (Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium; sp.)
-----------------------------------------------------XTRIEAV
RYRPILDSRGNKTVEAEVTTD-DG---GFGRAAAPSGASTGEHEAVELPVGE--------
---AIAAGRERIAPRLEGR-EFAGDQRGVDAALH-AADDTTD-----F--SAVGANVAVA
TSMAAAKAAADVLGVHTYQHL-----GGALR----------GRNFPVPLGNVLGGGAHAA
-DATAIQEFLVAATGAPSVRQAVFANAAVHQRVKDRLDDD-GVPAAK-GDEGAWAPSI-D
DATAFDVVAGAAAEVADEFG--------FD--VRLGLDLAAAERY---DGDEYVF-----
-----GDDRRSTAAQIEYVAGL---VSEYD-LAYVEDPLDENDFEAFAELTDRV---GDE
TLVCGDDLFVTNTERLQRGIDAGAANSILVKPNQIGTLTDAVDAIELATRNGYDAVVSHR
SGETEDTTIAHLAVATDAPFIKTGAVG-GERTAKLNELIRIADEA---------------
---------------
