>Saccharomyces
--------GG---UU-G-CG-GCCAU-AU-CUACCAGAAA-GCACCGUUC
UCCGUC-CGAUCAACUGUAGUUAAGCUGGUAAGAGCCUG--ACCG-----
-----A-GUAGUGUAGUG----GGU-GACCAUA-CGCGAAAC--UCA-G-
GUGCUGC--AA-UCu-----------------------------
 
>Candida
--------GG---UU-G-CG-GCCAU-AU-CUAGCAGAAA-GCACCGUUC
CCCGUU-CGAUCAACCGUAGUUAAGCUGCUAAGAGCAAU--ACCG-----
-----A-GUAGUGUAGUG----GGA-GACCAUA-CGCGAAAC--UAU-U-
GUGCUGC--AA-UCu-----------------------------
 
>Nosema
---------G---AU-A-CG-Guuauauuu--ACUGAAAA-CCACCGGAA
CCCAUC-AGAACUCC---------GAAGUUAAACCAGUA--UGAG--C-U
UAAUUA-GUACUAAGAAG----GGA-GACCACU-UGGGAACG--UUG-G-
GUGGua--------------------------------------
 
>Zea
--------GG---AU-G-CG-AUCAU-AC-CAGCACUAAA-GCACCGGAU
CCCAUC-AGAACUCC---------GAAGUUAAGCGUGCU--UGGG--C-G
AGAGUA-GUACUAGGAUG----GGU-GACCUCC-UGGGAAGU--CCU-C-
GUGUUGC--AU-UC------C-----------------------
 
>Dictyostelium
guau------------A-CG-GCCAU-AC-UAGGUUGGAA-ACACAUCAU
CCCGUU-CGAUCUGA---------UAAGUAAAUCGACCU--CAGG--CCu
u-CCAA-GUACUCUGGUU----GGA-GACAACA-GGGGAACA--UAG-G-
GUGCUGU--AU-ACu-----------------------------
 
>Euglena
---------G---AGuA-CG-GCCAU-AC-UACCGGGAAU-ACACCUGAA
CCCGUU-CGAUUUCA---------GAAGUUAAGCCGGGuuaGGCC--CAG
UUAGU----ACU-GAGUG----GGC-GACCACU-UGGGAACA--CUG-G-
GUGCUGU--AC-GCuu----------------------------
 
>Cryptosporidium
--------GC---AA-U-CG-GCCAU-AC-UACAUCGAAU-AUACCGGAU
CCCAUC-AGAACUCC---------GAAGUCAAGCGGUGU--AAGG--U-U
CGGUUA-GUACUAGGGUG----GGG-GACCACC-UGGGAAGA--CCA-GA
AUGUCGA--UC-GC------CU-C--------------------
 
>Caenorhabditis
--------GC---UU-A-CG-ACCAU-AU-CACGUUGAAU-GCACGCCAU
CCCGUC-CGAUCUGG---------CAAGUUAAGCAACGU--UGAG--U-C
CAGUUA-GUACUUGGAUC----GGA-GACGGCC-UGGGAAUC--CUG-G-
AUGUUGU--AA-GCu-----------------------------
 
>Drosophila
--------GC---CA-A-CG-ACCAU-AC-CACGCUGAAU-ACAUCGGUU
CUCGUC-CGAUCACC---------GAAAUUAAGCAGCGU--CGGG--C-G
CGGUUA-GUACUUAGAUG----GGG-GACCGCU-UGGGAACA--CCG-C-
GUGUUGU--UG-GC------Cu----------------------
 
>Xenopus
--------GC---CU-A-CG-GCCAU-AC-CACCCUGAAA-GUGCCCGAU
AUCGUC-UGAUCUCG---------GAAGCCAAGCAGGGU--CGGG--C-C
UGGUUA-GUACUUGGAUG----GGA-GACCGCC-UGGGAAUA--CCA-G-
GUGUCGU--AG-GCuu----------------------------
 
>Cryptobranchus
--------GC---CU-A-CG-GCCAU-AC-CACCCUGAAU-GCGCCCGAU
CUCGUC-UGAACUCA---------GAAGCUAAGCAGGCU--UGGG--C-C
UGGUUA-GUACUUGGAUG----GGA-GACUGCC-UGGGAAUA--CCA-G-
GUGCUGU--AG-GCuuu---------------------------
 
>Homo
--------GU---CU-A-CG-GCCAU-AC-CACCCUGAAC-GCGCCCGAU
CUCGUC-UGAUCUCG---------GAAGCUAAGCAGGGU--CGGG--C-C
UGGUUA-GUACUUGGAUG----GGA-GACCGCC-UGGGAAUA--CCG-G-
GUGCUGU--AG-GCuuu---------------------------
 
>Gelidium
--------AC---AU-U-CG-GCCAU-AC-UAAGUCGACAuGUACCCGAU
CCCAUCCCGAACUCG---------GAAGUCAAGUCGCUU--CAGG--C-C
GGGUUA-GUACUGAGGUG----AGG-GAUCACU-CGGGAAUC--CCC-G-
GUGCCGA--AU-Gu------------------------------
 
>Amoebidium
--------GG---UU-A-CG-GCCAU-AC-CUAGCAGAAA-GCACCCCAU
CUCGUC-CGAUCUGG---------GAAGUUAAACUGCUA--UGGG--C-G
UGGUUA-GUACUGCGGUG----GGG-GACCACG-CGGGAAUA--CCA-C-
GUGCUGU--AA-UCu-----------------------------
 
>Physarum
--------GG---AU-G-CG-GCCAU-AC-UAAGGAGAAA-GCACCUCAU
CCCGUC-CGAUCUGA---------GAAGUUAAGCUCCUU--CAGG--C-G
UGGUUA-GUACUGGGGUG----GGG-GACCACC-UGGGAAUC--CCA-C-
GUGCUGC--AU-UCuu----------------------------
 
>Desulfurococcus
uGC---CC-G---AC-C-CG-GCCAU-AG-UGGCCGGGCA-ACACCCGGU
CUCGUUUCGAACCCG---------GAAGUUAAGCCGGCC--ACGU--CAG
A--ACG-GCCGUGAGGUC----CGA-GAGGCCU-CGCAGCCG--UUC-U-
GAGCUGG--GA-UC------GGGCACC-----------------
 
>Sulfolobus
-----GCC-C---AC-C-CG-GUCAC-AG-UGAGCGGGCA-ACACCCGGA
CUCAUUUCGAACCCG---------GAAGUUAAGCCGCUC--ACGU--UAG
U--GGG-GCCGUGGAUAC----CGU-GAGGAUC-CGCAGCCC--CAC-U-
AAGCUGG--GA-UG------GGuuuu------------------
 
>Methanothermobacter
guu-----------G-G-CG-GUCAU-GG-CGUGGGGUUU-AUACCUGAU
CUCGUUUCGAUCUCA---------GUAGUUAAGUCCUGC--UGCG--UUG
UGGGUGuGUACUGCGGuuuuuu------GCu-G-UGGGAAGC--CCA-CU
UCACUGC--CA-GA------CA-A--------------------
 
>Campylobacter
AU------GU---CC-G-UG-AUUAU-AC-AGAUGUGGAA-ACGCCUUGC
UCCAUCCCGAACCAA---------GAAGCUAAGCACAUC-----------
---------------GUG----GGU-GAu--------GAUACuaCGC-C-
UUACUGG--CA-GG------GGGAAaguagcucauugCGGacuu
 
>Thermoplasma
--------GG---CA-A-CG-GUCAU-AG-CAGCAGGGAA-ACACCAGAU
CCCAUUCCGAACUCG---------ACGGUUAAGCCUGCU--GCGU--A-U
UGCGUU-GUACUGUAUGC----CGC-GAGGGUA-CGGGAAGC--GCA-A-
UAU---------GCuguuacCA-Cu-------------------
 
>Pyrobaculum
-GC---CC-CuaACC-C-GG-CCAUA-GG-CGCCGGUGAU-ACGCCCGGU
CUCAUC-AGAACCCG---------GAAGCUAAGGCCGGC--GCCG--CGC
UCGGGA-GUACUGGGCUC----CGC-GAGGGCC-CGGGAAAC--CGG-C-
GUGCUGG--GA-GG------GGGCuu------------------
 
>Nanoarchaeum
guuuCGugGG---AG---GG-CCAUA-GC-GGCCCGGGAA-CCACCCGUA
CCCAUCUCGAACACG---------GAAGUUAAGCCGGGC--CGCG--UCC
CGAGUG-GUACUGCC--C----CGC-GAAGGGG-UGGGAAGC--UCG-G-
GAU---------GC------CC----------------------
 
>Methanococcus
u----GAC-A---UA-A-CG-GUCAA-AG-CGGAGGUGUA-ACAUCCGAU
CCCAUCCCGAUCUCG---------GAAAUUAAGCCCUCC--AGCG--Auu
cuuuAA-GUACU-----------GC-UAUCUAG-UGGGAACA--AAGUG-
ACGCCGU--UA-GU------CA-C--------------------
 
>Methanothermococcus
u----GAU-A---UA-A-CG-GUCAU-AG-CGGAGGAGCC-ACAUCCGAU
CCCGUCCCGAUCUCG---------GAAAUUAAGCCCUCC--AGCG--AUA
CCCUAA-GUACU-----------GC-CAUUUGG-UGGGAACA--GGGUG-
ACGCUGU--UG-AU------CA-C--------------------
 
>Archeoglobus
AU------GC---CG-A-CG-GUCAU-AG-GACGGGGGAA-ACACCCGGA
CUCAUUCCGAACCCG---------GAAGUUAAGCCCCGU--UCCGucCCG
C--ACA-GUACUGUGUUC----CGA-GAGGGCA-CGGGAACU--GCG-G-
GAACCGU--CG-GCuu----------------------------
 
>Methanothermus
--------GGU-ACG-G-CG-ACCAU-AG-CGGGGGGGCC-ACACCUGAA
CCCGUUCCGAUCUCA---------GAAGUUAAGCCCCCC--UGCG--UUG
GAGGUG-GUACUGCA--A----CGU-UAGuu-G-CGGGAAGC--CUC-CA
ACGUCGC--CG-GC------CC-A--------------------
 
>Pyrococcus
--------GGU-ACG-G-CG-GUCAU-AG-CGGGGGGGCC-ACACCCGGU
CUCAUUUCGAACCCG---------GAAGUUAAGCCCCCC--AGCG--AUC
CCGGCU-GUACUGCCCUC----CGA-GAGGGGG-CGGGAACC--GGG-G-
ACGCCGC--CG-GC------CA----------------------
 
>Thermococcus
--------GGU-ACG-G-CG-GUCAU-AG-CGGCGGGGUC-ACACCCGGU
CUCGUUUCGACCCCG---------GAAGUUAAGCCCGCC--AGCG--AUC
CCGGUU-GUACUGCCCUC----CGG-GAGGGGG-CGGGAACC--GGG-G-
ACGCCGC--CG-GC------CA-C--------------------
 
>Methanospirillum
u-----CA-A---UA-G-CG-GCCAC-AG-CAGGUGUGUC-ACACCCGUU
CCCAUUCCGAACACG---------GAAGUUAAGACACCU--CACG--UGG
AUGACG-GUACUGAGGUA----CGC-GAGUCCU-CGGGAAAU--CAU-CC
UCGCUGCuauuguu------------------------------
 
>Halorubrum
--------GU---AG-G-CG-GCCAA-AG-CGGCAGGGAA-AGACCCGUA
CCCAUUCCGAACACG---------GAAGUGAAGCCUGCC--AGCG--UAC
CAGCUA-GUACUGGAGUG----GGA-GACCCUC-UGGGAGCG--CUG-GU
UCGCCGC--CU-AC------UC----------------------
 
>Natrinema
uu----------ACG-G-CG-GCCAC-AG-CGGCGAGGUA-CCUCCCGUA
CCCAUCCCGAACACG---------GAAGAUAAGCUCGCC--UGCG--UUU
CGGUCA-GUACUGGAGUG----GGC-GACCCUC-UGGGAACC--CCG-AU
UCGCCGC--CA-CC------ACUC--------------------
 
>Haloferax
uu----------AAG-G-CG-GCCAG-AG-CGGUGAGGUU-CCACCCGUA
CCCAUCCCGAACACG---------GAAGUUAAGCUCACC--UGCG--UUC
UGGUCA-GUACUGGAGUG----AGC-GAUCCUC-UGGGAAAU--CCA-GU
UCGCCGC--CC-Cu------------------------------
 
>Halobacterium
uu----------AAG-G-CG-GCCAU-AG-CGGUGGGGUU-ACUCCCGUA
CCCAUCCCGAACACG---------GAAGAUAAGCCCGCC--UGCG--UUC
CGGUCA-GUACUGGAGu------GC-GAGCCUC-UGGGAAAU--CCG-GU
UCGCCGC--CU-ACu-----------------------------
 
>Haloarcula
uu-----------AG-G-CG-GCCAC-AG-CGGUGGGGuugCCUCCCGUA
CCCAUCCCGAACACG---------GAAGAUAAGCCCACC--AGCG--UUC
CGGGGA-GUACUGGAGUG----CGC-GAGCCUC-UGGGAAAC--GCG-GU
UCGCCGC--CA-CC------------------------------
 
>Methanolobus
--------GG---UG-G-CG-GCCAU-AG-CGGCGGGGCA-AUUCCUGUA
CCCAUCCCGAACACA---------GAAGAUAAGCCCGCC--UGCGuuCUA
U--ACU-GUACUAAAGUA----UGA-GAGUCuuuGGGAAAUA--UGG-A-
ACGCUGC--CA-CC------AA-C--------------------
 
>Methanosarcina
--------GG---AGuuuGGCGCCAU-AG-CGGCAGUGUA-ACUCCUGUA
CCCAUCCCGAACACA---------GUAGAUAAGCCUGCC--CGCG--UUC
CUUACU-GUACUGAAGUG----UGC-GAGCCUU-CGGGAACU--CUG-GA
UCGCUGC--CA-UA------CU-CACC-----------------
 
>Methanosarcina.v
-----GAU-C---UG-G-CA-GCCAU-AG-CGGCAGGUGU-AAUCCUGUA
CCCAUCCCGAACACA---------GUAGAUAAGCCUGCC--CGCG--UUC
Cuu------------GCCuguaCUG-AAGUGUG-CGAGCUUC--GGG-A-
ACUCUGGauCGuGC------CAuau------------CAGu---
 
>Streptomyces
guuu---------CG-G-UG-GUCAU-AG-CGUUAGGGAA-ACGCCCGGU
UACAUUCCGAACCCG---------GAAGCUAAGCCUUAC--AGCG--CCG
AUGGU----ACU-GCAGG----GGG-GACCCUG-UGGGAGAG--UAG-G-
ACGCCGC--CG-AA------CA----------------------
 
>Escherichia
ug-----C-C---UG-G-CG-GCCGU-AG-CGCGGUGGUC-CCACCUGAC
CCCAUGCCGAACUCA---------GAAGUGAAACGCCGU--AGCG--CCG
AUGGUA-Gu-----GUGG----GGU-CUCCCCA-UGCGAGAG--UAG-G-
GAACUGC--CA-GG------CAu---------------------
 
>Flavobacterium
u-----------AAG-G-UG-GUUAU-UG-CGGCGGGGCU-CGACCUCUU
CCCAUCCCGAACAGA---------GUAGUUAAGCCCGCC--UGCG--CAG
AUGGU----ACU-GCAGuuau-----------G-UGGGAGAG--UAU-G-
UCGUCGC--Cuuuc------------------------------
 
>Chlamydia
-------C-U---UG-G-UG-AUAAU-AG-AGAGAGGGAA-ACACCUGAC
ACCAUUCCGAACUCA---------GAAGUUAAGCCUCUG--AUCG--CUG
AUGGU----ACuau---A----CAC-AAGAGUA-UGGGAGAG--UAG-G-
UCGUCGC--CA-AG------CAu---------------------
 
>Aquifex
--C---CC-C---UG-G-UG-GCCAU-AG-CGGGGGGGAA-ACACCCGGU
CCCAUUCCGAACCCG---------GCAGUUAAGCCCCCC--AGCG--CCG
AUGAU----ACU-GUGCC----GGC-AGCGGCA-CGGGAAAG--UAG-G-
UCGCUGC--CA-GG------GG----------------------
 
>Thermotoga
au-----C-C---CC-G-GGUGCCGAuACuGGGGCGGGAA-ACACCCGGU
UCCAUUCCGAACCCG---------GCCGUUAAGCCGCCC--UGGG--CCG
AUGGUA-Gu----AUGGG----GGC-AGCCCCA-UGCGAGAG--UAG-G-
UAGCGCC--CG-GG------GAu---------------------
 
>Agrobacterium
----CGAC-C---UG-G-UG-GUCAU-CG-CGGGGCGGCU-GCACCCGUU
CCCUUUCCGAACACG---------GCCGUGAAACGCCCC--AGCG--CCA
AUGGU----ACuu----C----GUCuCAAGACG-CGGGAGAG--UAG-G-
UCGCUGC--CA-GGucu---------------------------
 
>Thermus
aau---CC-C---CC-G-UG-CCCAU-AG-CGGCGUGGAA-CCACCCGUU
CCCAUUCCGAACACG---------GAAGUGAAACGCGCC--AGCG--CCG
AUGGU----ACU-GGGCG----GGC-GACCGCC-UGGGAGAG--UAG-G-
UCGGUGC--GG-GG------GAu---------------------
 
>Geobacillus
-------C-C---UA-G-UG-GUGAU-AG-CGGAGGGGAA-ACACCCGUU
CCCAUCCCGAACACG---------GAAGUUAAGCCCUCC--AGCG--CCG
AUGGUA-GUU----GGGG----CCA-GCGCCCC-UGCAAGAG--UAG-G-
UCGCUGC--UA-GG------C-----------------------
 
>Bacillus
uuu-----------G-G-UG-AUGAU-GG-CAGAGAGGUC-ACACCCGUU
CCCAUACCGAACACG---------GAAGUUAAGCUCUCU--AGCG--CCG
AUGGUA-GUU----GGGA----CCuu--GUCCC-UGUGAGAG--UAG-G-
ACGUCGC--CA-AG------C-----------------------
 
>Spirochaeta
-------C-C---UG-G-UG-AUCAU-AG-CGAAGAGGUC-CCACCCGUU
CCCAUCCCGAACACG---------GAAGUUAAGCUCUUC--AGCG--CCG
AUGGU----ACU-GCuauu-------------G-CGGGAGAG--UAG-G-
UCGUCGC--CA-GG------Cu----------------------
 