>beetle
------MGQLISLYKYYTTRTDDPDPLTTLTSREVFLVQSSWDPIKKD--LTG-YGVQLL
LFLFKKYPEEQQNF------PFRDMPFEELGASKKFHAHCSNVMYAVDSIIDSLKD----
GELLVN---ILEKIGRNHHRNT---V-KPISFWHVKETMLEFFKKMM----NDETLK-AW
DKALQVAFGVVAKELDKKN--------------------
>cyto-beetle
------MGIITSTLSYYMTKTNDPDPITGLTSRDRYVIQTSWAPVKKD--LTG-NGVALL
LLYFEKFPATKNYF------VFKDVPNEKLKTDKKFHAHCNSVMVTLDSLIANLND----
GELIVS---LLEKLGKNHKRHG---I-KDDAYDQLKETVIELFSSFM----TKEELE-TW
DKLLKVAFSVIIKYL------------------------
>honeybee
------MGTFLRFLGISSSDDNRIDQATGLTERQKKLVQNTWAVVRKD--EVA-SGIAVM
TAFFKKYPEYQRYFT-----AFMDTPLNELPANKRFQAHCAGVITALNNVIDFLHD----
PGLMEA---SLIGLVERHKKRG---Q-TKEEFQNLKEVMLEVLRQALGKQYTPEVAE-AW
NKTLDMMFGKIYQVFAS----------------------
>hemo-tunicate-1
---------------------------MPFTDEELKLLRDSWDEVKKLG-MKE-VGLHIF
TGLLNAAPSLRTLFYTIDLPDEEELTIDVMRENKKVVAHATRIANAISKFIKFLDQ----
PDELEK---LLTSLGESHARRQ---V-DPESFEYVAPVILSVIGGHLKLPSNSPTLQ-AW
VKAYGVLRNGIVSAMEA----------------------
>hemo-tunicate-3
---------------------------MSLTSEQVVLLRSSWQTIGKLG-MSN-VGLAVL
HRLFNDVPETLPFFHSVLSP-TQQTEIEVLKSNAKVVRHASRVGLSIDKIINLLDN----
GEELVK---YLLFLGQVHVKRS---I-PRKYFSAMGPVLLSVISAVLEKDLDAPVMQ-AW
ATAYGVIEQGIIDGM------------------------
>leghemo-pea
---------------------------MGFTEKQEALVNSSWELFKQN--PS--YSVLFY
TIILKKAPAAKGMFS------FLKDSAEVVD-SPKLQAHAEKVFGMVHDSAIQLRA----
SGEVVLGDAT---LGAIHIQKG---V-VDPHFVVVKEALLETIKEAS-GEKWSEELSTAW
EVAYEGLASAIKKAMN-----------------------
>leghemo-rice
----------------MALVEDNNAVAVSFSEEQEALVLKSWAILKKD--SAN-IALRFF
LKIFEVAPSASQMFS------FLRNSDVPLEKNPKLKTHAMSVFVMTCEAAAQLRK----
AGKVTVRDTTLKRLGATHLKYG---V-GDAHFEVVKFALLDTIKEEVPADMWSPAMKSAW
SEAYDHLVAAIKQEMKPAE--------------------
>neuro-zebrafish
--------------------------MEKLSEKDKGLIRDSWESLGKNK--VP-HGIVLF
TRLFELDPALLTLFS---YSTNCGDAP-ECLSSPEFLEHVTKVMLVIDAAVSHLDD----
LHTLED---FLLNLGRKHQAVG---V-NTQSFALVGESLLYMLQSSLGPAYTTSLRQ-AW
LTMYSIVVSAMTRGWAKNGEHKSN---------------
>neuro-human
--------------------------MERPEPE---LIRQSWRAVSRSP--LE-HGTVLF
ARLFALEPDLLPLFQ---YNCRQFSSPEDCLSSPEFLDHIRKVMLVIDAAVTNVED----
LSSLEE---YLASLGRKHRAVG---V-KLSSFSTVGESLLYMLEKCLGPAFTPATRA-AW
SQLYGAVVQAMSRGWD--GE-------------------
>myo-polychaete
--------------------------MAGLSGADIAVIRSTWAKVQGSGSATD-IGRSIF
IKFFELDPAAQNEFP---CKGESLAAL---KTNVLLGQHGAKFMEYITTAVNGLDDY---
AGKAHG---PLTELGSRHKTRG---T-TPANFGKAGEALLAILASVVGGDFTPAAKD-AW
TKVYNTISSTMQAAL------------------------
>hemo-polychaete-4
---------------------------MGLSAAQRQVVASTWKDIAGSDNGAG-VGKECF
TKFLSAHHDIAAVFG---FSG---------ASDPGVADLGAKVLAQIGVAVSHLGD----
EGKMVA---EMKAVGVRHKGYGYKHI-KAEYFEPLGASLLSAMEHRIGGKMTAAAKD-AW
AAAYADISGALISGLQS----------------------
>cyto-human
---MEKVPGEMEIERR--------ERSEELSEAERKAVQAMWARLYANCEDV---GVAIL
VRFFVNFPSAKQYFSQFK----HMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKV
SSVLAL-------VGKAHALKHKV---EPVYFKILSGVILEVVAEEFASDFPPETQR-AW
AKLRGLIYSHVTAAYKEVGWVQQVPNATTPPATLPSSGP
>cyto-fish
MSHREPPPPQLAVQRRDVDGQDGPERAEPLSDTEREMIRDAWGHVYKNCEDV---GVSIL
IRFFVNFPSAKQYFSQFQ----DMEEPEEMERSSQLRHHACRVMNALNTVVENLHDPEKV
SSVLAV-------VGRAHAVKHKV---EPMYFKILSGVILEVLCEDFPEFFTADVQL-VW
SKLMATVYWHVTGAYTDVGWLQVSSSAV-----------
>hagfish
-------------MSA--------HGIARTTEGERAAVRASWAVLMKDYEHA---GVQIL
DKFFKANPAAKPFFTKMK----DLHTLEDLASSADARWHVERIIQAVNFAVINIEDREKL
SNKFVK-------LSQDHIEEFHV--TDPQYFMILSQTILDEVEKRN-GGLSGEGKS-GW
HKVMTIICKMLKSKY------------------------
>lamprey
----------MPIVDS--------GSVPALTAAEKATIRTAWAPVYAKYQST---GVDIL
IKFFTSNPAAQAFFPKFQ----GLTSADQLKKSMDVRWHAERIINAVNDAVVAMDDTEKM
SLKLRE-------LSGKHAKSFQV---DPQYFKVLAAVIVDTVLP---------GDA-GL
EKLMSMICILLRSSY------------------------
>hemo-alpha-shark
----------------------------VLSAADKTAIKHLTGSLRTNAEAW---GAESL
ARMFATTPSTKTYFSKFT----DFSANGK-----RVKAHGGKVLNAVADATDHLDN---V
AGHLDP-------LAVLHGTTLCV---DPHNFPLLTQCILVTLAAHL-TELKPETHC-AL
DKFLCEVATALGSHYR-----------------------
>hemo-alpha-human
---------------------------MVLSPADKTNVKAAWGKVGAHAGEY---GAEAL
ERMFLSFPTTKTYFPHF-----DLSHGSA-----QVKGHGKKVADALTNAVAHVDD---M
PNALSA-------LSDLHAHKLRV---DPVNFKLLSHCLLVTLAAHLPAEFTPAVHA-SL
DKFLASVSTVLTSKYR-----------------------
>hemo-beta-human
--------------------------MVHLTPEEKSAVTALWGKV--NVDEV---GGEAL
GRLLVVYPWTQRFFESF-G---DLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDN---L
KGTFAT-------LSELHCDKLHV---DPENFRLLGNVLVCVLAHHFGKEFTPPVQA-AY
QKVVAGVANALAHKYH-----------------------
>hemo-beta-shark
---------------------------VHWTGEEKALVNAVWTKT--DHQAV---VAKAL
ERLFVVYPWTKTYFVKFNG---KFHASDS-----TVQTHAGKVVSALTVAYNHIDD---V
KPHFVE-------LSKKHYEELHV---DPENFKLLANCLEVELGHALHKEFTPEVQA-AW
SKFSNVVVDALSKGYH-----------------------
>myo-human
---------------------------MGLSDGEWQLVLNVWGKVEADIPGH---GQEVL
IRLFKGHPETLEKFDKFK----HLKSEDEMKASEDLKKHGATVLTALGGILKKKGH---H
EAEIKP-------LAQSHATKHKI---PVKYLEFISECIIQVLQSKHPGDFGADAQG-AM
NKALELFRKDMASNYKELGFQG-----------------
>myo-shark
--------------------------------VDWEKVNSVWSAVESDLTAI---GQNIL
LRLFEQYPESQNHFPKFK----N-KSLGELKDTADIKAQADTVLSALGNIVKKKGS---H
SQPVKA-------LAATHITTHKI---PPHYFTKITTIAVDVLSEMYPSEMNAQVQA-AF
SGAFKIICSDIEKEYKAANFQG-----------------
>HbI-Lucina
---------------------------MSLSAAQKDNVKSSWAKASAAWGTA---GPEFF
MALFDAHDDVFAKFSGLF----KGAAKGTVKNTPEMAAQAQSFKGLVSNWVDNLDNAGAL
EGQCKT-------FAANHKARGIS----AGQLEAAFKVLAGFMKSY------GGDEG-AW
TAVAGALMGMIRPNM------------------------
>HbII-Lucina
---------------------------TTLTNPQKAAIRSSWSKFMDNGVSN---GQGFY
MDLFKAHPETLTPFKSLF----GGLTLAQLQDNPKMKAQSLVFCNGMSSFVDHLDDN-ML
VVLIQK-------MAKLHNNRGIR----ASDLRTAYDILIHYMEDHN--HMVGGAKD-AW
EVFVGFICKTLGDYMKELS--------------------
>drosophila
-----------------------------MNSDEVQLIKKTWEIPVATPTDS---GAAIL
TQFFNRFPSNLEKFP------FRDVPLEELSGNARFRAHAGRIIRVFDESIQVLGQ----
DGDLEKLDEIWTKIAVSHIPRTVS----KESYNQLKGVILDVLTAACS---LDESQAATW
AKLVDHVYAIIFKAIDDDGNA------------------
>myo-snail
----------------------------SLQPASKSALASSWKTLAKDAATIQNNGATLF
SLLFKQFPDTRNYFTHFG-----NMSDAEMKTTGVGKAHSMAVFAGIGSMIDSMDDADCM
NGLALK-------LSRNHIQRKIG----ASRFGEMRQVFPNFLDEALGGGASGDVKG-AW
DALLAYLQDNKQAQAL-----------------------
>HbA-blood_clam
----------MADEEQIAKAVFKEAKALCDSDAAKENLRSSFKILANDIESS---GLQLM
KNLFTSHPDTLGYFAR-------FKDVSLGKQNWQLRGHAITLMYALMNFVDALDEPDRL
KCVVLK-------FAVNHNNRSIS----PQVFGKINGPMDLLLKQRMGKYYNRETAN-AW
KQLVGVVQAALTTPN------------------------
>myo-Dolabella
----------------------------ALSAAEAEVVAKSWGPVFANKDAN---GDNFL
IALFEAYPDSPNFFADFK-----GKSIADIRASPKLRNVSSRIVSRLNEFVSSAADAGKM
AAMLDQ-------FSKEHAGFGVG----SQQFQNVSAMFPGFVASIAAP---PAGADAAW
GKLFGLIIDAMKKAGK-----------------------
>midge-8
-------------------------AVTPMSADQLALFKSSWNTVKHN-------EVDIL
YAVFKANPDIQAKFPQFAG-----KDLDSIKDSADFAVHSGRIVGFFSEVIGLIGN----
PENRPALKTLIDGLASSHKARG----IEKAQFEEFRASLVDYLSHHLDWN---DTMKSTW
DLALNNMFFYILHALEVAQ--------------------
